Optimal Frequency to Screen Celiac Disease amongst Patients with Type 1 Diabetes Mellitus: A Multicenter Study

Autor: Hadis Ebrahimzadeh, Homa Ilkhanipoor, Fatemeh Sadat Mirrashidi, Daniel Zamanfar, Mahin Hashemipour, Nosrat Ghaemi, Fatemeh Aghamahdi, Atefeh Raoofat, Anis Amirhakimi, Somayyeh Hashemian, Hossein Moravej, Negar Yazdani, Peyman Eshraghi, Samaneh Noroozi Asl, Majid Vares Vazirian
Rok vydání: 2021
Předmět:
Zdroj: Primary Care Diabetes. 15:1100-1103
ISSN: 1751-9918
DOI: 10.1016/j.pcd.2021.08.011
Popis: Aims Celiac disease (CD) is frequent amongst patients with type 1 diabetes mellitus (T1DM). Since there is a disagreement on the optimal interval and frequency to perform screening tests for CD among diabetic patients, this study aimed to evaluate these issues amongst patients with T1DM. Methods This retrospective cohort study was conducted in seven referral diabetic centers in different cities of Iran from January 2020 to January 2021. Data belonging to 106 patients who were affected by both T1DM and CD was collected. The time interval between CD diagnosis and diabetes (IBCD), the age of diabetes onset, and any associated diseases, symptoms, and family history of T1DM and CD were recorded and analyzed. Results Results show that 45% of the patients with CD were diagnosed during the first year of diabetes onset; furthermore, 18% and 16% of the patients with CD were diagnosed in the second or third year after being diagnosed with diabetes. In addition, another 18% of patients with CD were diagnosed during the fourth till the eighth year after diabetes onset. Moreover, there was a negative relationship between the age of T1DM diagnosis and IBCD. Most participants were asymptomatic at the time of CD diagnosis. Conclusions Screening tests to detect CD amongst patients with T1DM should continue for at least eight years after the initial T1DM diagnosis, especially those affected at a younger age.
Databáze: OpenAIRE
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