Intra-operative methadone effect on quality of recovery compared with morphine following laparoscopic gastroplasty: a randomised controlled trial

Autor: L. H. Navarro e Lima, L. A. Mattar, João Paulo Jordão Pontes, F. R. Braz, Norma Sueli Pinheiro Módolo, J. A. G. Sousa
Přispěvatelé: Santa Genoveva Hospital Complex, Universidade Estadual Paulista (Unesp), Queens University
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Popis: Made available in DSpace on 2020-12-12T01:32:15Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01 The effect of intra-operative intravenous methadone on quality of postoperative recovery was compared with morphine after laparoscopic gastroplasty. We included 137 adult patients with a body mass index > 35 kg.m−2 who underwent bariatric surgery. Patients were allocated at random to receive either intra-operative methadone (n = 69) or morphine (n = 68). All patients received the same postoperative care and analgesia. The primary outcome of postoperative quality of recovery was assessed using the Quality of Recovery-40 questionnaire total score 24 h after surgery. Secondary outcomes were assessed in the post-anaesthesia care unit the night of the day of surgery (T1), in the morning after surgery (T2); and at night on the day following surgery (T3). The median (IQR [range]) total Quality of Recovery-40 questionnaire score of 194 (190–197 [165–200]) was higher (p
Databáze: OpenAIRE