A development of atheromatous plaque is restricted by characteristic arterial wall structure at the carotid bifurcation
| Autor: | Osamu Ohtani, Shunro Endo, Toru Masuoka, Nakamasa Hayashi, Hideki Origasa, Emiko Hori, Naoya Kuwayama, Yutaka Hirashima, Hideo Hamada |
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| Rok vydání: | 2008 |
| Předmět: |
Carotid Artery Diseases
Male medicine.medical_specialty medicine.medical_treatment Carotid endarterectomy Severity of Illness Index Cadaver Internal medicine medicine.artery Carotid bifurcation Humans Medicine Arterial wall Common carotid artery Aged Aged 80 and over business.industry Dissection Anatomy Middle Aged Elastic artery Atherosclerosis Case-Control Studies cardiovascular system Muscular artery Cardiology Female Surgery Endothelium Vascular Neurology (clinical) Internal carotid artery Tunica Media business Carotid Artery Internal |
| Zdroj: | Surgical Neurology. 69:586-590 |
| ISSN: | 0090-3019 |
| DOI: | 10.1016/j.surneu.2007.05.033 |
| Popis: | Background It is said atheromatous plaque is located very focally, but there have been few reports regarding this matter. Various aspects of the pathogenesis of the development of atheromatous plaque at the carotid bifurcation have previously been discussed. We have noted the correlation of plaque localization with characteristics of the cervical carotid artery wall. Methods Morphological and histopathologic changes in the carotid bifurcation were examined in 72 cadaver cases with or without atheromatous plaque. We determined the level at which the wall structure changed to muscular artery from elastic artery and analyzed its influence on the development of atheromatous plaque. Result Atheromatous plaques at the distal site of the ICA extended within 0 to 37 mm from the carotid bifurcation. The proximal side of the CCA more than 5 mm away from the bifurcation was elastic artery, whereas the distal side of the ICA more than 15 mm from the bifurcation was muscular artery. The area of the carotid bifurcation between elastic artery and muscular artery was a transitional zone. Approximately 80% of them were located within 15 mm, and these areas were coincident with the transitional zone. Conclusion Most atheromatous plaque was located in the transitional zone. The arterial wall structure is related to the development of atheromatous plaque at the cervical carotid bifurcation. |
| Databáze: | OpenAIRE |
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