Clinical usefulness of serum neopterin in children with juvenile idiopathic arthritis
| Autor: | Barbara Kamińska, Magdalena Lange, Katarzyna Plata-Nazar, Katarzyna Sznurkowska, Małgorzata Szumera, Grazyna Łuczak, Agnieszka Szlagatys-Sidorkiewicz, Anna Liberek |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Exacerbation Clinical Biochemistry markers Arthritis Inflammation Biochemistry autoimmune disorders Elevated serum chemistry.chemical_compound exacerbation remission Internal medicine Medicine Juvenile Crystallography business.industry Serum neopterin Neopterin Serum concentration medicine.disease Endocrinology chemistry QD901-999 Molecular Medicine medicine.symptom business disease activity |
| Zdroj: | Pteridines, Vol 26, Iss 2, Pp 69-72 (2015) |
| ISSN: | 2195-4720 0933-4807 |
| DOI: | 10.1515/pterid-2015-0003 |
| Popis: | The aim of this study was to analyze the usefulness of the serum concentration of neopterin (NPT) as a marker of juvenile idiopathic arthritis (JIA). The study included 67 children with JIA (36 girls and 31 boys), aged between 3.8 and 17.9 years (mean 13.7±3.4 years), and 105 healthy controls (47 girls and 58 boys) of similar age, with no evidence of acute or chronic inflammation. Serum NPT was determined immunoenzymatically. The median serum concentration of NPT and prevalence of elevated serum NPT (>11 nmol/L) were significantly higher in children with JIA than in the controls: 6.044 vs. 4.734 nmol/L (p11 nmol/L (50% vs. 0%, p |
| Databáze: | OpenAIRE |
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