Neurosarcoidosis Presentation as Adipsic Diabetes Insipidus Secondary to a Pituitary Stalk Lesion and Association with Anti-NMDA Receptor Antibodies
Autor: | Bayron Alexander Sandoval Bonilla, Marco Antonio Rodríguez Florido, Jose Malagón Rangel, Arturo Olascoaga Lugo, José Gabriel Solís |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Pathology
medicine.medical_specialty medicine.diagnostic_test Heart block business.industry Central nervous system Neurosarcoidosis Case Report 030204 cardiovascular system & hematology medicine.disease Lesion 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Pituitary Stalk Lesion Biopsy medicine Sarcoidosis Neurology. Diseases of the nervous system medicine.symptom General Agricultural and Biological Sciences business RC346-429 030217 neurology & neurosurgery Encephalitis |
Zdroj: | Case Reports in Neurological Medicine, Vol 2020 (2020) Case Reports in Neurological Medicine |
ISSN: | 2090-6676 2090-6668 |
Popis: | Sarcoidosis is a multisystemic inflammatory disease of unknown cause. It is characterized by the presence of noncaseating granuloma on a biopsy specimen. Clinical presentation varies across case report series with myriad of symptoms ranging from fever, respiratory symptoms, and skin lesions, or atypical symptoms like heart block or neurological symptoms. Hence, we report the case of a 22-year-old woman with encephalitis, a pituitary mass, and adipsic diabetes insipidus. The diagnostic approach did not end on the biopsy of the lesion, which reported noncaseating granulomas; on the contrary, it was the beginning of a path to exclude other causes of the central nervous system granulomas that ended with the diagnosis of the isolated central nervous system sarcoidosis. Also, we report the first proven association between anti-NMDA receptor antibodies and sarcoidosis. |
Databáze: | OpenAIRE |
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