Temporal FST genome scans: the case of partially selfing populations
| Autor: | Navascues, Miguel, Becheler, Arnaud, Gay, Laurène, Ronfort, Joëlle, Vitalis, Renaud |
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| Přispěvatelé: | Centre de Biologie pour la Gestion des Populations (UMR CBGP), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Université de Montpellier (UM)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Évolution, génomes, comportement et écologie (EGCE), Université Paris-Sud - Paris 11 (UP11)-IRD-Centre National de la Recherche Scientifique (CNRS), Amélioration génétique et adaptation des plantes méditerranéennes et tropicales (UMR AGAP), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), European Society of Evolutionnary Biology (ESEB). INT. |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | 2. Joint Congress on Evolutionary Biology (EVOLUTION 2018) 2. Joint Congress on Evolutionary Biology (EVOLUTION 2018), Aug 2018, Montpellier, France. 2018 2. Joint Congress on Evolutionary Biology (EVOLUTION 2018), Montpellier, FRA, 2018-08-19-2018-08-22 Sex uncovered: the evolutionary biology of reproductive systems Sex uncovered: the evolutionary biology of reproductive systems, Apr 2018, Roscoff, France. 1 p., 2018 Sex uncovered: the evolutionary biology of reproductive systems, Roscoff, FRA, 2018-04-23-2018-04-27 |
| Popis: | In an isolated population, allele frequencies change through time because of selection (acting on specific loci) and genetic drift (acting on the whole genome). Theeffective size of a population (which characterizes the strength of genetic drift) can be estimated from temporal changes in allele frequencies at presumably neutral markers. Furthermore, generating the expected distribution of differentiation statistics conditionally on the inferred effective size, allows to test for the homogeneity of locus-specific estimates of temporal differentiation. Outlier loci, for which the extent of temporal differentiation is unlikely to be explained by the inferred rate of genetic drift, can therefore be characterized. However, self-fertilization may pose a problem for the detection of loci under selection. Selfing indeed reduces the effective size of populations and the effective recombination rate between loci, thereby promoting hitch-hiking. Here, we first propose a new test for the homogeneity of temporal differentiation at many loci, based on temporal measures of FST. We then investigate the effect of partial selfing on the power to detect selected loci and the false discovery rate , using simulated populations. In addition, we characterize the footprints of selection along a chromosome containing a selected site for a range of selfing rates. |
| Databáze: | OpenAIRE |
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