Dynamics of PHA-induced immune response and plasma carotenoids in birds: should we have a closer look?
| Autor: | Clotilde Biard, Sébastien Motreuil, Clotilde Hardy, Jérôme Moreau |
|---|---|
| Přispěvatelé: | Biogéosciences [Dijon] ( BGS ), Université de Bourgogne ( UB ) -AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique ( CNRS ), Konrad Lorenz Institute for Ethology, Austrian Academy of Sciences ( OeAW ), Biogéosciences [UMR 6282] [Dijon] (BGS), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS), Austrian Academy of Sciences (OeAW) |
| Rok vydání: | 2009 |
| Předmět: |
0106 biological sciences
Male Physiology [ SDV.IMM.IA ] Life Sciences [q-bio]/Immunology/Adaptive immunology 01 natural sciences Songbirds [ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/Symbiosis Body Size bill colour Carotenoid chemistry.chemical_classification 0303 health sciences immunocompetence Beak Ornaments blackbird [SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunology medicine.symptom Immunocompetence medicine.medical_specialty cell-mediated immune response Inflammation chemical and pharmacologic phenomena Aquatic Science Biology 010603 evolutionary biology 03 medical and health sciences Immune system Immunity Internal medicine medicine Animals Phytohemagglutinins Molecular Biology Ecology Evolution Behavior and Systematics 030304 developmental biology [ SDE.BE ] Environmental Sciences/Biodiversity and Ecology Cell-mediated immune response Carotenoids Endocrinology chemistry Insect Science Immunology carotenoid-based signals Animal Science and Zoology [SDE.BE]Environmental Sciences/Biodiversity and Ecology Mitogens Limited resources [SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis |
| Zdroj: | Journal of Experimental Biology Journal of Experimental Biology, Cambridge University Press, 2009, 212 (Pt 9), pp.1336-1343. 〈10.1242/jeb.028449〉 Journal of Experimental Biology, The Company of Biologists, 2009, 212 (Pt 9), pp.1336-1343. ⟨10.1242/jeb.028449⟩ |
| ISSN: | 0022-0949 1477-9145 |
| DOI: | 10.1242/jeb.028449〉 |
| Popis: | SUMMARY Allocation trade-offs of limited resources are thought to ensure the honesty of sexual signals and are often studied using controlled immune challenges. One such trade-off between immunity and ornaments is that involving carotenoids. Phytohemagglutinin (PHA)-induced immune response is a widely used immune challenge, yet more details on the underlying physiological mechanisms and potential costs are needed. We investigated the temporal dynamics of PHA-induced immune response and associated changes in blood carotenoids, body mass and a carotenoid-based coloured signal. We found variation in individual response patterns to PHA after peak swelling was reached, with birds showing either a rapid or a slow subsequent decrease in swelling, suggesting variation in the duration of the immune response and/or inflammation. Body mass did not affect immune response. Plasma carotenoids followed a transient decrease closely matching the dynamics of the swelling. The peak of the immune response was negatively related to initial plasma carotenoid levels and positively correlated to the relative decrease in plasma carotenoids. Individual variation in duration of the swelling could be partly explained by plasma carotenoids; high initial carotenoid levels were associated with a slower decrease of the swelling. These contradictory effects of carotenoids suggest a complex role in the immune response. Bill colour was positively correlated to initial plasma carotenoid concentration but it did not predict or change as a consequence of immune response to PHA. Bill colour thus reflects medium- or long-term quality rather than immediate quality. Taking into account the dynamics of the immune response and that of associated physiological parameters would thus yield new insights into our interpretation of variation in PHA response. |
| Databáze: | OpenAIRE |
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