Clinical Characteristics of Anti-aquaporin 4 Antibody Positive Optic Neuritis in Japan
| Autor: | Masato Wakakura, Kenji Inoue, Keiko Tanaka, Hitoshi Ishikawa, Akiko Yamagami, Toshiyuki Takahashi |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
biology business.industry Medical record Original Articles medicine.disease 03 medical and health sciences Ophthalmology 0302 clinical medicine Anti aquaporin 4 antibody Maintenance therapy Internal medicine 030221 ophthalmology & optometry medicine biology.protein Optic neuritis In patient sense organs Neurology (clinical) Antibody business 030217 neurology & neurosurgery |
| Zdroj: | Neuro-Ophthalmology. 43:71-80 |
| ISSN: | 1744-506X 0165-8107 |
| Popis: | To investigate the clinical characteristics and the effectiveness of maintenance therapy of anti-AQP4 antibody positive optic neuritis in Japanese patients, medical records from 69 patients (103 eyes) were retrospective reviewed. The status of relapse in patients who received maintenance therapy following acute therapy was compared with that before maintenance therapy in patients who started maintenance therapy ≥6 months after acute therapy. In Japan, anti-AQP4 antibody positive optic neuritis was characterized by older onset age and poor visual outcome. The yearly rate and total number of relapses were lower when maintenance therapy was followed immediately after acute therapy. |
| Databáze: | OpenAIRE |
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