Prognostic impact of angiographic findings, procedural success, and timing of percutaneous coronary intervention in cardiogenic shock

Autor: Sabell, Tuija, Banaszewski, Marek, Lassus, Johan, Nieminen, Markku S., Tolppanen, Heli, Jäntti, Toni, Kataja, Anu, Hongisto, Mari, Køber, Lars, Sionis, Alessandro, Parissis, John, Tarvasmäki, Tuukka, Harjola, Veli-Pekka, Jurkko, Raija, Universitat Autònoma de Barcelona
Přispěvatelé: HUS Heart and Lung Center, Department of Medicine, Helsinki University Hospital Area, University of Helsinki, Kardiologian yksikkö, Clinicum, HUS Emergency Medicine and Services, Department of Diagnostics and Therapeutics
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Male
medicine.medical_specialty
Acute coronary syndrome
OCCLUSION
medicine.medical_treatment
Short Communication
Short Communications
Shock
Cardiogenic
030204 cardiovascular system & hematology
Revascularization
Coronary Angiography
Percutaneous coronary intervention
03 medical and health sciences
0302 clinical medicine
TERM MORTALITY
Internal medicine
Medicine
Diseases of the circulatory (Cardiovascular) system
Humans
030212 general & internal medicine
Myocardial infarction
cardiovascular diseases
PREDICTORS
Cardiogenic shock
ARTERY
Aged
business.industry
ELEVATION MYOCARDIAL-INFARCTION
PCI
Thrombolysis
Middle Aged
medicine.disease
Prognosis
3. Good health
3121 General medicine
internal medicine and other clinical medicine
RC666-701
Conventional PCI
Cardiology
Female
Cardiology and Cardiovascular Medicine
business
TIMI
Zdroj: ESC Heart Failure
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
ESC Heart Failure, Vol 7, Iss 2, Pp 768-773 (2020)
Sabell, T, Banaszewski, M, Lassus, J, Nieminen, M S, Tolppanen, H, Jäntti, T, Kataja, A, Hongisto, M, Køber, L, Sionis, A, Parissis, J, Tarvasmäki, T, Harjola, V P & Jurkko, R 2020, ' Prognostic impact of angiographic findings, procedural success, and timing of percutaneous coronary intervention in cardiogenic shock ', ESC heart failure, vol. 7, no. 2, pp. 768-773 . https://doi.org/10.1002/ehf2.12637
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
ISSN: 2055-5822
Popis: Altres ajuts: This study was supported by grants from the Finnish Foundation for Cardiovascular Research, and Aarne Koskelo Foundation, Helsinki, Finland. Roche Diagnostics provided kits for the analysis of NT-proBNP and TnT. The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; or decision to submit the manuscript for publication. Tuija Sabell (néeJavanainen) received following personal research grants: Acute Coronary Syndromes and secondary prevention grant from the Finnish Cardiac Society, grant supported by Astra Zeneca and grants from Paavo Nurmi Foundation and Paavo Ilmari Ahvenaisen säätiö. Dr Lassus has served on an advisory board for Boehringer Ingelheim, Medix Biochemica, Novartis, Servier, and Vifor Pharma and received lecture fees from Bayer, Boehringer Ingelheim, Pfizer, Novartis, Orion Pharma, and Vifor Pharma. Dr Parissis has received honoraria from Novartis and Orion Pharma. Urgent revascularization is the mainstay of treatment in acute coronary syndrome (ACS) related cardiogenic shock (CS). The aim was to investigate the association of angiographic results with 90-day mortality. Procedural complications of percutaneous coronary intervention (PCI) were also examined. This CardShock (NCT01374867) substudy included 158 patients with ACS aetiology and data on coronary angiography and complications during PCI procedure. Survival analysis was conducted with Kaplan-Meier curves and Cox regression analysis. Median age was 67 ± 11 years, and 77% were men. During 90-day follow-up, 66 (42%) patients died. Patients with one-vessel disease (n = 49) had lower mortality than patients with two-vessel (n = 59) or three-vessel (n = 50) disease (25% vs. 48% vs. 52%, P = 0.011). Successful revascularization [Thrombolysis in Myocardial Infarction (TIMI) Flow 3 post-PCI) was achieved more often in survivors than non-survivors (81% vs. 60%, P = 0.019). The median symptom-to-balloon time was 340 (196-660) minutes, with no difference between survivors and non-survivors. In multivariable mortality analysis, multivessel disease (HR 2.59, CI 1.29-5.18) and TIMI flow
Databáze: OpenAIRE
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