Cytology of Ki-1 (CD-30) positive large cell lymphoma
| Autor: | C. J. L. M. Meyer, L. A. Noorduyn, P. Heerde |
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| Rok vydání: | 1990 |
| Předmět: |
Antigens
Differentiation T-Lymphocyte Pathology medicine.medical_specialty Lymphoma B-Cell Histology Immunocytochemistry Ki-1 Antigen Biology Lymphoma T-Cell Immunophenotyping Pathology and Forensic Medicine Diagnosis Differential Antigens CD Antigens Neoplasm Cytology Biomarkers Tumor medicine Humans Anaplastic large-cell lymphoma Large cell Large-cell lymphoma Antibodies Monoclonal General Medicine medicine.disease Lymphoma Non-Hodgkin's lymphoma Antigens Differentiation B-Lymphocyte Lymphoma Large B-Cell Diffuse Differential diagnosis |
| Zdroj: | Cytopathology. 1:297-304 |
| ISSN: | 1365-2303 0956-5507 |
| Popis: | To study the cytomorphology of Ki-1 (CD-30) positive anaplastic large cell lymphoma, imprints and fine needle aspirates from a total of 20 of these tumours were collected. The results show that these tumours have a highly pleomorphic and variable picture, which can be easily confused with other poorly differentiated large cell tumours. Typical morphological differences between the B-cell and T-cell variety were found. B-cell tumours more often showed nuclear multilobation, a fine, hypochromatic chromatin pattern, and many lymphoglandular bodies. T-cell tumours more often displayed multinucleation, window nuclei, and a hyperchromatic coarse chromatin pattern. The diagnosis of anaplastic large cell Ki-1 positive lymphoma, B-cell type or T-cell type, should be included in the differential diagnosis of any large cell tumour of uncertain origin with mainly dissociated tumour cells. Immunocytochemistry is recommended to establish the correct diagnosis. |
| Databáze: | OpenAIRE |
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