Ultrasensitive Diagnosis for an Anthrax-Protective Antigen Based on a Polyvalent Directed Peptide Polymer Coupled to Zinc Oxide Nanorods
| Autor: | Moon-Young Yoon, Vinayakumar Gedi, Joungmok Kim, Hae-Chul Park, Sung-Hwan Han, Hye-Yeon Park |
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| Rok vydání: | 2011 |
| Předmět: |
chemistry.chemical_classification
Detection limit Antigens Bacterial Nanotubes Materials science Mechanical Engineering Anthrax toxin Bacterial Toxins chemistry.chemical_element Peptide Biosensing Techniques Polymer Zinc Conjugated system Combinatorial chemistry chemistry Mechanics of Materials Organic chemistry General Materials Science Nanorod Zinc Oxide Peptides Biosensor |
| Zdroj: | Advanced Materials. 23:5425-5429 |
| ISSN: | 0935-9648 |
| DOI: | 10.1002/adma.201103284 |
| Popis: | A flexible poly-D-lysine polymer conjugated with different target-binding peptides is demonstrated with an ultralow concentration detection limit compared to those of other conventional detection systems. This polyvalent directed peptide polymer (PDPP) exhibits increased binding affinity and detects anthrax protective antigen at low levels using a well-known zinc oxide nanorod detection system. |
| Databáze: | OpenAIRE |
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