The adhesin structures involved in the adherence of group B streptococci to human vaginal cells
| Autor: | Bulgakova Tn, J Jelinková, Grabovskaya Kb, Miloš Rýc |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Hot Temperature
Ultraviolet Rays Neuraminidase Sialidase medicine.disease_cause Microbiology Group B Bacterial Adhesion Streptococcus agalactiae chemistry.chemical_compound medicine Humans Trypsin reproductive and urinary physiology biology General Medicine bacterial infections and mycoses Streptococcaceae biology.organism_classification In vitro Pepsin A Sialic acid Bacterial adhesin chemistry Glutaral Vagina biology.protein bacteria Female |
| Zdroj: | Folia microbiologica. 31(5) |
| ISSN: | 0015-5632 |
| Popis: | The adherence of group B streptococci (GBS) of serotypes Ia, II and III to human vaginal cells was studied in vitro. The adherence was not dependent on the viability of bacteria; killing of GBS by UV irradiation or glutaraldehyde treatment did not inhibit the adherence. Killing of GBS by heating to 56 degrees C for 1 h led to a pronounced decrease of adherence, demonstrating the thermosensitivity of the GBS structures involved. The protein nature of these structures was proved by a significant reduction of adherence after pretreatment of GBS with trypsin or pepsin. Pretreatment of GBS with sialidase had no influence on the adherence. Such a pretreatment of vaginal cells caused an increase of adherence showing that the receptors on epithelial cells may be partly masked by sialic acid. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink