| Autor: |
Ensiyeh Ghasemian-Shirvan, Ruxandra Ungureanu, Lorena Melo, Kim van Dun, Min-Fang Kuo, Michael A. Nitsche, Raf L. J. Meesen |
| Přispěvatelé: |
GHASEMIAN SHIRVAN, Ensiyeh, Ungureanu, Ruxandra, Melo, Lorena, VAN DUN, Kim, Kuo, Min-Fang, Nitsche, Michael A., MEESEN, Raf |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Brain Sciences; Volume 13; Issue 1; Pages: 137 |
| Popis: |
One of the most visible effects of aging, even in healthy, normal aging, is a decline in motor performance. The range of strategies applicable to counteract this deterioration has increased. Transcranial direct current stimulation (tDCS), a non-invasive brain stimulation technique that can promote neuroplasticity, has recently gained attention. However, knowledge about optimized tDCS parameters in the elderly is limited. Therefore, in this study, we investigated the effect of different anodal tDCS intensities on motor sequence learning in the elderly. Over the course of four sessions, 25 healthy older adults (over 65 years old) completed the Serial Reaction Time Task (SRTT) while receiving 1, 2, or 3 mA of anodal or sham stimulation over the primary motor cortex (M1). Additionally, 24 h after stimulation, motor memory consolidation was assessed. The results confirmed that motor sequence learning in all tDCS conditions was maintained the following day. While increased anodal stimulation intensity over M1 showed longer lasting excitability enhancement in the elderly in a prior study, the combination of higher intensity stimulation with an implicit motor learning task showed no significant effect. Future research should focus on the reason behind this lack of effect and probe alternative stimulation protocols. We thank Nicole Rück and master students for their kind help in recruiting elderly participants in Germany and Belgium, respectively. We really appreciate our colleagues: Tobias Blanke, Tobias Klimek, Nina Abich, Mohsen Mosayebi-Samani in Germany and Mark Geraerts in Belgium for their technical support to build up the experimental setup. We are grateful to Klaus Golka and Jan G. Hengstler for medical screening of participants, and Hannah Schade and Benedikt Glinski for their help with psychological test assessment. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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