Plasma bisphenol a and phthalate levels in children with cerebral palsy: a case-control study

Autor: Özlem Tezol, Sıddıka Songül Yalçin, Anıl Yirün, Aylin Balci Özyurt, Çetin Okuyaz, Pınar Erkekoğlu
Rok vydání: 2022
Předmět:
Zdroj: International journal of environmental health research.
ISSN: 1369-1619
Popis: The case-control study aimed to evaluate potential sources of exposure and the plasma concentrations of bisphenol A (BPA) and phthalates in prepubertal children having cerebral palsy (CP) and healthy control. Blood samples of 68 CP and 70 controls were analyzed for BPA, di-(2-ethylhexyl)-phthalate (DEHP), mono-(2-ethylhexyl)-phthalate (MEHP), and dibutyl phthalate (DBP). BPA and DBP levels were similar in groups. The median DEHP and MEHP levels of the children with CP were significantly lower than those of the controls (p = 0.035, p 0.001, respectively). Exposure to plastic food containers/bags, personal care hygiene products, household cleaners, wood/coal stove heating, and city water supplies were associated with increased odds of higher BPA and phthalate levels in children with CP. In conclusion, potential exposure sources for BPA and phthalates differ in children with CP and healthy controls, and children with CP are not exposed to higher levels of BPA and phthalates.
Databáze: OpenAIRE