ABO-incompatible auxiliary partial orthotopic liver transplant for late-onset familial amyloid polyneuropathy
| Autor: | Naoki Hattori, I Yokoyama, T Kobayashi, Gen Sobue, A Nakao, Manabu Doyu, Yukio Ando, Hirohisa Watanabe, K. Misu |
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| Rok vydání: | 2002 |
| Předmět: |
Male
congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty medicine.medical_treatment Liver transplantation Gastroenterology ABO Blood-Group System ABO blood group system Internal medicine Preoperative Care Living Donors medicine Humans Amyloid Neuropathies Familial biology business.industry Amyloidosis Plasmapheresis Middle Aged medicine.disease Liver Transplantation Surgery Transplantation Transthyretin Neurology Blood Group Incompatibility biology.protein Neurology (clinical) Age of onset business Polyneuropathy Immunosuppressive Agents |
| Zdroj: | Journal of the Neurological Sciences. 195:63-66 |
| ISSN: | 0022-510X |
| DOI: | 10.1016/s0022-510x(01)00678-5 |
| Popis: | A 60-year-old Japanese man with late-onset familial amyloid polyneuropathy type I (FAP transthyretin Met30) showed clinical improvement following auxiliary partial orthotopic liver transplantation (APOLT) from an ABO-incompatible living related donor. Preoperatively, plasmapheresis and immunosuppressant drugs were used to reduce serum antibodies against the donor's ABO type. APOLT was chosen so the residual liver could sustain the patient in the event of hyperacute rejection. OLT is applicable to late-onset FAP transthyretin Met30, and APOLT can be considered in ABO-incompatible cases. |
| Databáze: | OpenAIRE |
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