Squamous cell carcinoma arising in an area of long-standing necrobiosis lipoidica
| Autor: | Mark Tschuchnigg, Cathy Lim, Jake Lim |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
Pathology Histology Skin Neoplasms Early detection Dermatology Pathology and Forensic Medicine Malignant transformation Necrobiosis lipoidica Diabetes Complications Carcinoma Medicine Humans Basal cell Necrobiosis Lipoidica business.industry Anatomical pathology Nodule (medicine) Middle Aged medicine.disease Epidermoid carcinoma Carcinoma Squamous Cell Female medicine.symptom business |
| Zdroj: | Journal of cutaneous pathology. 33(8) |
| ISSN: | 0303-6987 |
| Popis: | Background: Squamous cell carcinoma in an area of chronic ulceration is a well-documented phenomenon. However, its occurrence arising de novo in an area of necrobiosis lipoidica is rare. Method: We report a case in a 53-year-old female who presented with a 2 month history of an erythematous nodule occurring in a plaque of necrobiosis lipoidica on the medical aspect of the right lower leg. She had a background of poorly controlled Type 1 diabetes. Results: Histopathological findings revealed a well-differentiated squamous cell carcinoma overlying an area of necrobiosis lipoidica. Treatment was by excision and split-thickness skin graft. Conclusion: Clinicians should be aware of malignant transformation within a plaque of necrobiosis lipoidica. Early detection will allow conservative treatment. |
| Databáze: | OpenAIRE |
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