Alkylation of 2-Phenyl-4-quinolones: Synthetic and Structural Studies
| Autor: | Anne-Marie Mariotte, Mohamed Hadjeri, Ahcène Boumendjel |
|---|---|
| Přispěvatelé: | Département de pharmacochimie moléculaire (DPM), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF) |
| Rok vydání: | 2001 |
| Předmět: |
Models
Molecular Magnetic Resonance Spectroscopy Alkylation Chemical Phenomena Bicyclic molecule Chemistry Physical 010405 organic chemistry Stereochemistry Chemistry 4-quinolones Regioselectivity General Chemistry General Medicine Nuclear magnetic resonance spectroscopy Quinolones 010402 general chemistry 01 natural sciences Chemical synthesis Mass Spectrometry 0104 chemical sciences Drug Discovery Indicators and Reagents [SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biology lipids (amino acids peptides and proteins) |
| Zdroj: | Chem. Pharm. Bull. Chem. Pharm. Bull., 2001, 49, pp.1352-1355 |
| ISSN: | 1347-5223 0009-2363 |
| Popis: | The alkylation of 2-phenyl-4-quinolones was investigated and showed that the N-alkylation versus O-alkylation is highly dependent on whether C-5 is hydroxylated or not. N-Alkylation is favoured by the presence of a 5-hydroxyl group. The synthetic and the NMR structural studies are reported. |
| Databáze: | OpenAIRE |
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