Sleep-related breathing disorders and gait variability: a cross-sectional preliminary study
| Autor: | Cédric Annweiler, Jean-Claude Barthélémy, Richard Camicioli, Olivier Beauchet, Frédéric Roche, Sébastien Celle |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Cross-sectional study Polysomnography STRIDE Gait disorders Walking Severity of Illness Index Body Mass Index Executive Function Sleep Apnea Syndromes Severity of illness Memory span medicine Humans Gait Depression (differential diagnoses) Aged medicine.diagnostic_test business.industry Sleep-related breathing disorders Cross-Sectional Studies Older adults Physical therapy Female France business Body mass index Research Article |
| Zdroj: | BMC Pulmonary Medicine |
| ISSN: | 1471-2466 |
| Popis: | Background Sleep-related breathing disorders (SRBDs) provoke cognitive and structural brain disorders. Because these disorders have been associated with unsafe gait characterized by an increase in stride-to-stride variability of stride time (STV), we hypothesised that SRBDs could be associated with an increased STV. The aim of this study was to examine the association between SRBDs and STV in French healthy older community-dwellers. Methods A total of 49 participants (mean age 69.6 ± 0.8years; 65.2% female) were included in this cross-sectional study. All participants, who were free of clinically diagnosed SRBDs before their inclusion, had a nocturnal unattended home-sleep assessment. There were separated in three group based on apnea + hypopnea index (AHI): AHI 30 defining moderate-to-severe SRBD. Coefficient of variation of stride time, which is a measure of STV, was recorded while usual walking using SMTEC® footswitches system. Digit span score was used as a measure of executive performance. Age, gender, body mass index (BMI), number of drugs daily taken, vision, proprioception, history of falls, depression symptoms, global cognitive functioning were also recorded. Results STV and BMI were higher in participants with mild SRBDs (P = 0.031 and P = 0.020) and moderate-to-severe SRBDs (P = 0.004 and P = 0.002) compared to non-SRBDs. STV positively correlated with AHI (P = 0.036). Lower (i.e., better) STV was associated with the absence of SRBDs (P = 0.021), while greater (i.e., worse) STV was associated with moderate-to-severe SRBD (P 0.06). Conclusion Our results show a positive association between STV and SRBDs, with moderate-to-severe SRBD being associated with greater gait variability. This association opens new perspectives for understanding gait disorders in older adults with SRBDs and opens the door to treatments options since SRBDs are potential treatable factors. |
| Databáze: | OpenAIRE |
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