Large outbreak of urogenital schistosomiasis acquired in Southern Corsica, France: monitoring early signs of endemicization?
| Autor: | H. Noël, J.-L. Termignon, M. Ruello, H. Barré-Cardi, J. Durand, Antoine Berry, Camille Pelat, M. Debruyne, Judith Fillaux, L. Ramalli, A. Maccary, P. Malfait, J.-D. Chiappini, C. Sommen, Jérôme Boissier, G. Chyderiotis |
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| Přispěvatelé: | Institut des Sciences Chimiques de Rennes (ISCR), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-Ecole Nationale Supérieure de Chimie de Rennes-Centre National de la Recherche Scientifique (CNRS), Interactions Hôtes-Pathogènes-Environnements (IHPE), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Perpignan Via Domitia (UPVD), Institut Européen des membranes (IEM), Université de Montpellier (UM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Centre National de la Recherche Scientifique (CNRS), Cellule Interrégionale d'Epidémiologie, Santé publique France, French Ministry of Health, Santé publique France - French National Public Health Agency [Saint-Maurice, France], Office de l'environnement de la Corse, CHU Toulouse [Toulouse], Centre de Physiopathologie Toulouse Purpan (CPTP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 2017 |
| Předmět: |
Microbiology (medical)
Adult Male medicine.medical_specialty Adolescent Early signs 030231 tropical medicine Early detection Corsica Schistosomiasis [SDV.MHEP.UN]Life Sciences [q-bio]/Human health and pathology/Urology and Nephrology Serology Disease Outbreaks 03 medical and health sciences Schistosomiasis haematobia Young Adult 0302 clinical medicine [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases Urogenital schistosomiasis Environmental health Medicine Urogenital Schistosomiasis Humans 030212 general & internal medicine Child ComputingMilieux_MISCELLANEOUS Aged [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases business.industry Transmission (medicine) [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE] Outbreak General Medicine Environmental Exposure Middle Aged medicine.disease 3. Good health Surgery Infectious Diseases Epidemiologic surveillance Parasitic Child Preschool [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie Female France business |
| Zdroj: | Clinical Microbiology and Infection Clinical Microbiology and Infection, Elsevier for the European Society of Clinical Microbiology and Infectious Diseases, 2018, 24 (3), pp.295-300. ⟨10.1016/j.cmi.2017.06.026⟩ Clinical Microbiology And Infection (1198-743X) (Elsevier Sci Ltd), 2018-03, Vol. 24, N. 3, P. 295-300 |
| ISSN: | 1469-0691 1198-743X |
| Popis: | International audience; Objectives: Clustered cases of urogenital schistosomiasis were reported in April 2014 among French and German tourists linked to exposure in the Cavu River, Southern Corsica, France, between 2011 and 2013. We set up national surveillance for autochthonous urogenital schistosomiasis to document the largest possible number of cases in order to identify potential sites of transmission and to determine the extent of the outbreak in France and Corsica.Methods:The early response consisted mostly of prohibiting swimming in the river, performing a nationwide serologic screening of all persons exposed to the river between 2011 and 2013 and treating confirmed cases. Physicians were asked to report all patients with one or more positive antischistosome serologic test. Cases were defined as occurring in a resident of France with serologic evidence of schistosomiasis or schistosome eggs in urine and no history of contact with freshwater in known endemic areas. We documented symptoms as well as place and time of exposure to freshwater for all subjects. To estimate the outbreak size, we modelled the effect of the 2014 nationwide screening on the 2011–2015 time series of serodiagnosed schistosomiasis cases using log-linear autoregression.Results: In 2014, a total of 106 autochthonous cases were reported, including 35 symptomatic infections. All patients had swum in the Cavu during summer 2013. Over 30 000 persons were likely screened for autochthonous schistosomiasis. The model-estimated outbreak size was 338 cases, including 36 serodiagnosed in 2015.Conclusions: Besides the 2013 outbreak, there is evidence of small-scale transmission in 2015 in Corsica. Early detection and control of recurrences requires raising community and medical awareness. |
| Databáze: | OpenAIRE |
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