The accuracy of cervicovaginal cytology in the detection of recurrent cervical carcinoma following radiotherapy
| Autor: | K.E. Free, R.G. Wright, Paul Shield, B. Daunter |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Uterine Cervical Neoplasms Cervix Uteri Adenocarcinoma Cytology Carcinoma medicine Humans Vaginal smear Cervix Vaginal Smears Cervical cancer business.industry Obstetrics and Gynecology medicine.disease Recurrent Cervical Carcinoma Surgery Radiation therapy medicine.anatomical_structure Oncology Vagina Carcinoma Squamous Cell Female Vaginal vault Neoplasm Recurrence Local business |
| Zdroj: | Gynecologic Oncology. 41:223-229 |
| ISSN: | 0090-8258 |
| DOI: | 10.1016/0090-8258(91)90313-t |
| Popis: | The accuracy of cervicovaginal cytology testing in the detection of recurrent cervical carcinoma was investigated by correlating clinical and histology records with cytology smear results for two groups of patients. All patients had been treated with radiotherapy, with or without pelvic surgery, for carcinoma of the uterine cervix. Abnormal cervicovaginal smear results were present for 45.7% ( 32 70) of patients with histologically diagnosed recurrent cervical carcinoma including a correct prediction of recurrent cervical carcinoma in 32.8% ( 23 70) of cases. A cytologic diagnosis of recurrent carcinoma was present for 48.9% ( 23 47) of cases with local recurrence. The positive predictive value for a histologic diagnosis of recurrent cervical carcinoma after a positive cytology report for a group of 61 patients was estimated to be 98.4%. A cytologic diagnosis of locally recurrent cervical carcinoma preceded clinical signs in 15 61 (24.6%) of cases. These results indicate that although cervicovaginal cytology after radiotherapy for cervical cancer does not have high sensitivity it is a reliable test for the diagnosis of local recurrence. Cytologic examination of the vaginal vault or cervix after treatment may thus provide an early diagnosis of tumor recurrence or persistence, in some cases prior to the onset of clinical signs. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|