When Does Quality of Life Improve After Liver Transplantation? A Longitudinal Prospective Study
| Autor: | Diogo Telles-Correia, António Barbosa, E. Mateus, Estela Monteiro, Inês Mega |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
Pediatrics medicine.medical_treatment Physical fitness Liver transplantation Liver disease Quality of life Preoperative Care medicine Humans Outpatient clinic Liver Diseases/psychology Longitudinal Studies Prospective Studies Prospective cohort study Transplantation Liver Diseases/physiopathology business.industry Liver Diseases Immunosuppression medicine.disease Liver Transplantation Surgery HCC CHBPT Liver Transplantation/psychology Liver Transplantation/physiology Mental Health Physical Fitness Quality of Life business Follow-Up Studies Liver Diseases/surgery |
| Zdroj: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação instacron:RCAAP CIÊNCIAVITAE |
| Popis: | Objectives. We sought to investigate the improvement in quality of life (mental and physical components) at 1 and 6 months after liver transplantation. Methods. A sample of liver transplant candidates (n 60), comprising consecutive patients attending outpatient clinics of a liver transplantation central unit (25% of the patients had familial amyloid polyneuropathy [FAP] and the remaining patents had chronic liver diseases), was assessed by means of the Short Form (SF)-36, Portuguesevalidated version, a self-rating questionnaire developed by the Medical Outcome Trust, to investigate certain primary aspects of quality of life, at 3 times: before, and at 1 and 6 months after transplantation. Results. We observed a significant improvement in quality of life (both mental and physical components) by 1 month after transplantation. Between the first month and the sixth month after transplantation, there also was an improvement in the quality of life (both mental and physical components), although only the physical components of quality of life was significantly improved. Conclusions. Our findings suggested that quality of life improved early after liver transplantation (1 month). Between the first and the sixth months, there only was a significant improvement in the physical quality of life. N OWADAYS, THE CALL to examine quality of life as it is affected by transplantation has became stronger, because transplantation technology and immunosuppression have lead to many kinds of transplants. The increasing prevalence of transplantation demands full consideration of the range of costs and benefits. Most studies have demonstrated that quality of life is improved by transplantation of patients with liver disease. 1‐4 Nevertheless, many authors debate when the improvement occurs. Most studies assess patients more than 6 months after transplantation. In contrast, the few studies that evaluate patient quality of life during the first months after transplantation report contradictory results, sometimes showing worsened patient quality of life (mental or physical dimensions). 5 The present study sought to investigate the improvement in quality of life (mental and physical components) at 1 and 6 months after liver transplantation. |
| Databáze: | OpenAIRE |
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