Chronic obstructive pulmonary disease severity and its association with obstructive sleep apnea syndrome: impact on cardiac autonomic modulation and functional capacity
| Autor: | Fabíola Paula Galhardo Rizzatti, Ramona Cabiddu, Flávia Cristina Rossi Caruso, Katiany Thays Lopes Zangrando, Audrey Borghi-Silva, Guilherme Peixoto Tinoco Arêas, Luiz Carlos Soares de Carvalho, Renata Trimer, Meliza Goi Roscani |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Health Status Pulmonary disease Blood Pressure Walk Test functional capacity 030204 cardiovascular system & hematology International Journal of Chronic Obstructive Pulmonary Disease Autonomic Nervous System Severity of Illness Index 03 medical and health sciences Electrocardiography Pulmonary Disease Chronic Obstructive 0302 clinical medicine Heart Rate Internal medicine Medicine Heart rate variability COPD Humans Prospective Studies Vagal tone Lung Original Research Aged COPD+OSAS Sleep Apnea Obstructive business.industry Hemodynamics OSAS Heart General Medicine Middle Aged medicine.disease respiratory tract diseases Obstructive sleep apnea Cross-Sectional Studies 030228 respiratory system Walk test Lung disease Cardiology Female Autonomic modulation business |
| Zdroj: | International Journal of Chronic Obstructive Pulmonary Disease |
| ISSN: | 1178-2005 |
| Popis: | Katiany Thays Lopes Zangrando,1 Renata Trimer,2 Luiz Carlos Soares de Carvalho Jr,1 Guilherme Peixoto Tinoco Arêas,1 Flávia Cristina Rossi Caruso,1 Ramona Cabiddu,1 Meliza Goi Roscani,3 Fabíola Paula Galhardo Rizzatti,3 Audrey Borghi-Silva1 1Cardiopulmonary Physiotherapy Laboratory, Physiotherapy Department, Federal University of São Carlos, São Carlos, São Paulo, Brazil; 2Physical Education and Health Department, University of Santa Cruz do Sul, Santa Cruz do Sul, Rio Grande do Sul, Brazil; 3Medicine Department, Federal University of São Carlos, São Carlos, São Paulo, Brazil Background: The study was conducted to determine the impact of chronic obstructive pulmonary disease (COPD) in association with obstructive sleep apnea syndrome (OSAS) on cardiac autonomic control and functional capacity. Subjects and methods: The study was a cross-sectional prospective controlled clinical study. Heart rate variability indices of 24 COPD (n = 12) and COPD+OSAS (n = 12) patients were evaluated and compared by electrocardiographic recordings acquired during rest, active postural maneuver (APM), respiratory sinus arrhythmia maneuver (RSA-m), and the 6-minute walk test (6MWT). Results: The COPD group presented higher parasympathetic modulation during APM when compared to the COPD+OSAS group (P = 0.02). The COPD+OSAS group presented higher sympathetic modulation during RSA-m when compared to the COPD group (P = 0.00). The performance during 6MWT was similarly impaired in both groups, despite the greater severity of the COPD group. Conclusion: Subjects with COPD+OSAS present marked sympathetic modulation, and the presence of OSAS in COPD subjects has a negative impact on functional capacity regardless of the severity of lung disease. Keywords: COPD, OSAS, COPD+OSAS, functional capacity |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|