VioBio lab adaptive optics: technology and applications by women vision scientists

Autor: Shrilekha Vedhakrishnan, Clara Benedi-Garcia, Carmen M. Lago, Lucie Sawides, Maria Vinas, Ana Gonzalez-Ramos, Mercedes Romero, Sara Aissati, Susana Marcos, Aiswaryah Radhkrishnan
Přispěvatelé: European Commission, Ministerio de Ciencia e Innovación (España), Ministerio de Economía y Competitividad (España), Comunidad de Madrid, Alcon, Essilor
Rok vydání: 2020
Předmět:
Zdroj: Digital.CSIC. Repositorio Institucional del CSIC
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ISSN: 1475-1313
Popis: 13 pags., 9 figs.
Purpose: Adaptive Optics allows measurement and manipulation of the optical aberrations of the eye. We review two Adaptive Optics set-ups implemented at the Visual Optics and Biophotonics Laboratory, and present examples of their use in better understanding of the role of optical aberrations on visual perception, in normal and treated eyes. Recent findings: Two systems (AOI and AOII) are described that measure ocular aberrations with a Hartmann-Shack wavefront sensor, which operates in closed-loop with an electromagnetic deformable mirror, and visual stimuli are projected in a visual display for psychophysical measurements. AOI operates in infrared radiation (IR) light. AOII is provided with a supercontiniuum laser source (IR and visible wavelengths), additional elements for simulation (spatial light modulator, temporal multiplexing with optotunable lenses, phase plates, cuvette for intraocular lenses-IOLs), and a double-pass retinal camera. We review several studies undertaken with these AO systems, including the evaluation of the visual benefits of AO correction, vision with simulated multifocal IOLs (MIOLs), optical aberrations in pseudophakic eyes, chromatic aberrations and their visual impact, and neural adaptation to ocular aberrations. Summary: Monochromatic and chromatic aberrations have been measured in normal and treated eyes. AO systems have allowed understanding the visual benefit of correcting aberrations in normal eyes and the adaptation of the visual system to the eye's native aberrations. Ocular corrections such as intraocular and contact lenses modify the wave aberrations. AO systems allow simulating vision with these corrections before they are implanted/fitted in the eye, or even before they are manufactured, revealing great potential for industry and the clinical practice. This review paper is part of a special issue of Ophthalmic & Physiological Optics on women in visual optics, and is co-authored by all women scientists of the research team.
This study has been supported by European Research Council Grant Agreement ERC‐2011‐AdG‐294099 and EUROHORCS EURYI‐05‐102‐ES to SM; Spanish Government grants FIS2005‐04382, FIS2008‐02065, FIS2011‐25637, FIS2014‐240920, FIS2017‐84753 (SM); Spanish Government Human Resource Programs PTA2017‐13787‐I (MR) and FPU Fellowships (MV, SA, LS), Marie Curie Initial Training Networks PITN‐GA‐2010‐264605 Opal (AR) and H‐2020‐MSCA‐ITN‐2015‐ETN‐MyFUN 675137; Comunidad Autónoma de Madrid Fundacion Madri+d Industrial Doctorate Program (CL) and Technical Support Personnel (AMG). Collaborative agreements with PhysIOL (Liège, Belgium), Alcon Research Labs (Fort Worth, Texas, USA) and Essilor International (France) have partially funded some of the results presented here.
Databáze: OpenAIRE
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