Seroprevalence and associated factors of HSV-2 infection among general population in Shandong Province, China

Autor:	Qing Pan, Tongsheng Chu, Zhang Yuan, Fanghui Fu, Xiaoling Wang, Hui Zhao, Fangfang Bao, Gongqi Yu, Aiqiang Xu, Honglei Wang, Pengcheng Huai, Guiye Niu, Dianchang Liu, Xiaoqiao Lang, Daina Liu, Xi'an Fu, Chuan Wang, Zhen Li, Yonghu Sun, Lele Sun, Furen Zhang, Zemin Chai, Hong Liu, Jian Liu, Furong Li, Zihao Mi, Bingni Zhou
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Adult Male 0301 basic medicine medicine.medical_specialty China Adolescent Herpesvirus 2 Human Sexual Behavior 030106 microbiology Population Seroprevalence Disease lcsh:Infectious and parasitic diseases Interviews as Topic Young Adult 03 medical and health sciences 0302 clinical medicine Seroepidemiologic Studies Surveys and Questionnaires Epidemiology Odds Ratio medicine Humans lcsh:RC109-216 030212 general & internal medicine education education.field_of_study business.industry Associated factors Herpes Simplex Odds ratio Middle Aged Confidence interval HSV-2 (herpes simplex virus type-2) Genital ulcer Cross-Sectional Studies Sexual Partners Infectious Diseases Tropical medicine Female medicine.symptom business Research Article Demography
Zdroj:	BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-9 (2019) BMC Infectious Diseases
ISSN:	1471-2334
DOI:	10.1186/s12879-019-3995-2
Popis:	Background Herpes simplex virus type-2 (HSV-2) infection is the main cause of genital ulcer disease and increases the risk of HIV acquisition. Little information is available regards the epidemiological characteristics of HSV-2 among general population in China. The aim of this study was to explore seroprevalence and associated factors of HSV-2 and provide information for design of HSV-2 control strategy in Shandong, China. Methods In this cross-sectional study, a total of 8074 persons, 18–49 years of age, were selected using multi-stage probability sampling to represent the general population of Shandong in 2016. Demographic data were collected through face-to-face interviews. Other variables were obtained by self-administered questionnaire surveys. Blood was collected for HSV-2 IgG detection with ELISA. Results A total of 7256 sexually-active participants were included in the analysis. The weighted seroprevalence of HSV-2 infection was 4.2% (95% confidence interval [CI], 3.2–5.3) in females, which was significant higher than that in males (2.7%; 95% CI, 1.1–4.2) (P = 0.04). The seroprevalence of HSV-2 was higher in individuals from eastern region (6.4%; 95% CI, 5.9–6.9) and urban areas (4.3%; 95% CI, 2.6–6.0) of Shandong than those from other regions (P
Databáze:	OpenAIRE
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