Critical evaluation of muscle mass loss as a prognostic marker of morbidity in critically ill patients and methods for its determination
| Autor: | Eduard Havel, Miroslav Kovarik, A. Patkova, Daniela Uramova, Zdenek Zadak, Vera Joskova, Simona Najpaverova, Miloslav Hronek |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Weakness
medicine.medical_specialty medicine.medical_treatment Critical Illness proteincatabolism Physical Therapy Sports Therapy and Rehabilitation 030204 cardiovascular system & hematology law.invention Body Mass Index 03 medical and health sciences 0302 clinical medicine law Intensive care Risk of mortality Medicine Humans Intensive care medicine Mechanical ventilation bodycomposition myolysis business.industry Rehabilitation Ultrasound lcsh:RM1-950 030229 sport sciences General Medicine Prognosis Intensive care unit muscleatrophy Muscle atrophy Survival Rate lcsh:Therapeutics. Pharmacology medicine.symptom Morbidity business Body mass index stressmetabolism |
| Zdroj: | Journal of Rehabilitation Medicine, Vol 50, Iss 8, Pp 696-704 (2018) |
| ISSN: | 1651-2081 1650-1977 |
| Popis: | Objective: Loss of muscle mass in critically ill patients is associated with serious consequences, such as prolonged mechanical ventilation, intensive care unit confinement, and higher mortality. Thus, monitoring muscle mass, and especially its decline, should provide a useful indicator of morbidity and mortality. Performing evaluations according only to body mass index is imperfect, therefore the aim of this article was to evaluate appropriate methods for muscle mass loss determination in ICU patients. Methods: For this review, the literature searches were conducted through Embase and Medline, PubMed and Google Scholar databases up to February 2018 for the following Medical Subject Headings terms muscle atrophy, protein catabolism, ICU-aquaired weakness, muscle muss loss, myolysis, critical illness, stress metabolism, computed tomography, magnetic resonance imaging, dual-energy X-ray absorptiometry, neutron activation analysis, anthropometric examination, determination of endogenous metabolites of the skeletal muscles, bioimpedance spectroscopy, ultrasound. Result: It appears that ultrasound, which is widely available in hospitals, is the most advantageous method. Muscle ultrasound is non-invasive, relatively inexpensive, and is a bedside method that is free of ionizing radiation. Furthermore, muscle ultrasound also seems to be valid in patients with severe fluid retention, which is a typical complication with other conventional methods. Conclusion: Early detection of critical illness neuromyo-pathy could be beneficial for improving the standards of intensive care, and thus reducing the risk of mortality in these patients. |
| Databáze: | OpenAIRE |
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