The effetcts of transcranial Direct Current Stimulation (tDCS) on idiopathic Hypersomnia: a pilot study
| Autor: | Luigi Ferini-Strambi, Virginia M. Borsa, Stela Musteata, Marco Zucconi, Andrea Galbiati, Sandro Iannaccone, Enrico Giora, Jubin Abutalebi |
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| Přispěvatelé: | Galbiati, A, Abutalebi, J, Iannaccone, S, Borsa, Vm, Musteata, S, Zucconi, M, Giora, E, Ferini-Strambi, L |
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Physiology medicine.medical_treatment Excessive daytime sleepiness Pilot Projects Stimulation Disorders of Excessive Somnolence Idiopathic Hypersomnia Audiology Transcranial Direct Current Stimulation Arousal 03 medical and health sciences 0302 clinical medicine medicine Humans 0501 psychology and cognitive sciences 050102 behavioral science & comparative psychology Narcolepsy Sleep disorder Transcranial direct-current stimulation 05 social sciences Cell Biology General Medicine medicine.disease Physical therapy medicine.symptom Psychology Neurocognitive 030217 neurology & neurosurgery After treatment |
| Zdroj: | ARCHIVES ITALIENNES DE BIOLOGIE. 154:1-5 |
| ISSN: | 0003-9829 |
| DOI: | 10.12871/00039829201611 |
| Popis: | Idiopathic Hypersomnia (IH) is a rare sleep disorder characterised by excessive daytime sleepiness (EDS) that leads to invalidating daytime consequences. Till now the treatment of IH has mirrored that of sleepiness in narcolepsy, and it is mainly focused on symptoms' management. In this study, we employed an anodal transcranic Direct Current Stimulation (tDCS) treatment in order to induce a shift toward arousal in IH patients' cortex during the day. Every patient underwent a 4 weeks treatment (3 stimulations per week, for a total of 12 stimulations over a period of 28 days), with an assessment at the baseline and after treatment aimed to the evaluation of subjective daytime sleepiness, neurocognitive functions, and attentional domain tested by means of the Attentional Network Task (ANT). The dependent variables of the ANT are accuracy and reaction times, which represent the objective outcome of our study. A significant effect of tDCS' treatment in reducing EDS was found. Besides the amelioration in subjective EDS, an objective improvement in reaction times in all conditions of the ANT, in particular in the more difficult component, was observed. Our results indicate that tDCS may foster the management of EDS in la improving also the attentional domain. |
| Databáze: | OpenAIRE |
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