Cascade fluorofunctionalisation of 2,3-unsubstituted indoles by means of electrophilic fluorination
| Autor: | Jean-Alexandre Richard, Danson Kwong Jia Ye, Eileen Lau Shuying, Charles W. Johannes, Tuan Minh Nguyen, Hung A. Duong, Fu Pincheng |
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| Rok vydání: | 2013 |
| Předmět: |
Sulfonamides
Indoles Halogenation Electrophilic fluorination Metals and Alloys Temperature chemistry.chemical_element General Chemistry Fluorine Nitrogen Catalysis Carbon Surfaces Coatings and Films Electronic Optical and Magnetic Materials Oxygen chemistry.chemical_compound chemistry Cascade Cyclization Indoline Materials Chemistry Ceramics and Composites Organic chemistry |
| Zdroj: | Chemical communications (Cambridge, England). 49(90) |
| ISSN: | 1364-548X |
| Popis: | Cascade fluorofunctionalisation of 2,3-unsubstituted indoles featuring the formation of C–C, C–F and C–O bonds via electrophilic fluorination using N-fluorobenzenesulfonimide is described. The use of an O-nucleophile tethered to the nitrogen of indoles enables the synthesis of polycyclic fluorinated indoline derivatives from simple precursors in 40–63% yields. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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