Scabies in a 14‐year‐old girl with superficial epidermolytic ichthyosis
| Autor: | Patricia Pérez-Feal, Igor Vázquez-Osorio, Nelmar Valentina Ortiz-Cabrera, Laura Sainz-Gaspar, Angela Hernández-Martín, Noelia Moreiras-Arias |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Adolescent media_common.quotation_subject Hyperkeratosis macromolecular substances Dermatology Scabies Ivermectin Epidermolytic Ichthyosis medicine Animals Humans Girl media_common Hyperkeratosis Epidermolytic integumentary system business.industry Complete remission Infant Keratosis medicine.disease Molecular analysis Pediatrics Perinatology and Child Health Female Keratin-2 Sarcoptes scabiei business medicine.drug |
| Zdroj: | Pediatric Dermatology. 39:305-306 |
| ISSN: | 1525-1470 0736-8046 |
| DOI: | 10.1111/pde.14867 |
| Popis: | A 14-year-old girl who reported generalized scaling and hyperkeratosis since age 1 year presented with severe pruritus of several months' duration. Scabies mites were detected, and molecular genetic analysis subsequently revealed a rare pathogenic variant in the keratin 2 (KRT2) gene, confirming a diagnosis of superficial epidermolytic ichthyosis. Treatment with oral ivermectin led to complete remission of symptoms. Disorders of keratinization can mimic clinical signs of scabies, leading to a delay in diagnosis. |
| Databáze: | OpenAIRE |
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