Effects of Sleep Deprivation on Acute Skeletal Muscle Recovery after Exercise
Autor: | Helton de Sá Souza, Marcus Vinicius Lucio dos Santos Quaresma, Murilo Dáttilo, Marcos Mônico-Neto, Carlos Ugrinowitsch, Nadine Marques Nunes Galbes, Sergio Tufik, Marco Túlio de Mello, Hanna Karen Moreira Antunes, Kil Sun Lee |
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Rok vydání: | 2019 |
Předmět: |
Adult
Male medicine.medical_specialty Hydrocortisone Physical Therapy Sports Therapy and Rehabilitation Isometric exercise Young Adult Internal medicine medicine Humans Eccentric Knee Testosterone Orthopedics and Sports Medicine Muscle Strength Exercise physiology Muscle Skeletal Creatine Kinase Exercise Cross-Over Studies biology Tumor Necrosis Factor-alpha business.industry Skeletal muscle Receptors Interleukin-6 Sleep in non-human animals Sleep deprivation Endocrinology medicine.anatomical_structure biology.protein Sleep Deprivation Creatine kinase medicine.symptom business Muscle Contraction Hormone |
Zdroj: | Medicine & Science in Sports & Exercise. 52:507-514 |
ISSN: | 1530-0315 0195-9131 |
Popis: | Purpose Sleep is considered essential for muscle recovery, mainly due to its effect on hormone secretion. Total sleep deprivation or restriction is known to alter not only blood hormones but also cytokines that might be related to skeletal muscle recovery. This study aimed to evaluate whether total sleep deprivation after eccentric exercise-induced muscle damage (EEIMD) modifies the profiles of blood hormones and cytokines. Methods In two separate conditions, with a crossover and randomized model, 10 men (age, 24.5 ± 2.9 yr; body mass index, 22.7 ± 2.3 kg·m) performed a unilateral EEIMD protocol that comprised 240 eccentric contractions of the knee extensor muscles using an isokinetic dynamometer. In one condition, a "muscle damage" protocol was followed by 48 h of total sleep deprivation and 12 h of normal sleep (DEPRIVATION). In the other condition, the same muscle damage protocol was conducted, followed by three nights of regular sleep (SLEEP). Isometric muscle voluntary contraction tests and blood samples were collected serially throughout the protocol and analyzed for creatine kinase, free and total testosterone, IGF-1, cortisol, tumor necrosis factor-alpha, interleukin (IL)-1beta, IL-6, receptor antagonist of IL-1 and IL-10. Results Muscle voluntary contraction and serum creatine kinase increased equally over the study period in both conditions. From the cytokines evaluated, only IL-6 increased in DEPRIVATION. No differences were detected in testosterone levels between conditions, but IGF-1, cortisol, and cortisol/total testosterone ratio were higher in DEPRIVATION. Conclusions Total sleep deprivation after EEIMD does not delay muscle strength recovery but modifies inflammatory and hormonal responses. |
Databáze: | OpenAIRE |
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