Management of hepatitis B virus infection, updated Swedish guidelines
| Autor: | Christian Kampmann, Gunnar Norkrans, Stephan Stenmark, Magnus Lindh, Ola Weiland, Maria Castedal, Karin Lindahl, Soo Aleman, Johan Westin, Rune Wejstål, Ann-Sofi Duberg, Björn Fischler, Anders Eilard |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Microbiology (medical) medicine.medical_specialty Hepatitis B virus Infectious Medicine medicine.medical_treatment 030106 microbiology antiviral treatment Infektionsmedicin Liver transplantation medicine.disease_cause Tenofovir alafenamide Antiviral Agents 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans 030212 general & internal medicine Liver damage Antiviral treatment Sweden Hepatocellular cancer Evidence-Based Medicine General Immunology and Microbiology business.industry General Medicine Hepatitis B medicine.disease digestive system diseases Chronic infection Infectious Diseases hepatocellular cancer surveillance Drug Therapy Combination chronic hepatitis prophylaxis business Biomarkers |
| Popis: | Despite access to effective antiviral drugs and vaccines, hepatitis B virus (HBV) infection remains a major health issue worldwide. HBV is highly infectious and may cause chronic infection, progressive liver damage, hepatocellular cancer (HCC) and death. Early diagnosis, proper management and timing of treatment are crucial. The Swedish Reference group for Antiviral Treatment (RAV) here provides updated evidence-based guidelines for treatment and management of HBV infection which may be applicable also in other countries. Tenofovir alafenamide (TAF) has been introduced as a novel treatment option and new principles regarding indication and duration of treatment and characterization of hepatitis B have been gradually introduced which justifies an update of the previous guidelines from 2007. Updated guidelines on HCC surveillance in HBV-infected patients, treatment and prophylaxis for patients undergoing liver transplantation as well as management of pregnant women and children with HBV infection are also provided. |
| Databáze: | OpenAIRE |
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