Bone Scintigraphy in Pembrolizumab-Induced Inflammatory Arthritis
| Autor: | Kazuaki Mori, Masato Tachi, Hirotaka Maruno, Masamichi Imai, Yuki Kosaka |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
musculoskeletal diseases
Male Pathology medicine.medical_specialty Inflammatory arthritis Pembrolizumab Technetium Tc 99m Medronate Antibodies Monoclonal Humanized Bone and Bones 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine Humans Radiology Nuclear Medicine and imaging Lung cancer Radionuclide Imaging Aged Inflammation medicine.diagnostic_test business.industry Arthritis General Medicine medicine.disease Hypertrophic osteoarthropathy Bone scintigraphy 030220 oncology & carcinogenesis Rheumatoid arthritis business |
| Zdroj: | Clinical nuclear medicine. 45(12) |
| ISSN: | 1536-0229 |
| Popis: | We present a novel report on the use of bone scintigraphy in pembrolizumab-induced inflammatory arthritis. A 70-year-old man with lung cancer complained about arthralgia after 7 courses of the pembrolizumab therapy. Tc-HMDP bone scintigraphy revealed symmetrically strong uptakes in the major distal joints of the upper and lower extremities, thereby clearly identifying them as the affected joints. The pattern of uptakes was not consistent with that of other pathophysiologies including bone metastases, hypertrophic osteoarthropathy, and rheumatoid arthritis. Tc-HMDP bone scintigraphy is more practical and cost-effective compared with PET to reveal the affected joints in pembrolizumab-induced inflammatory arthritis. |
| Databáze: | OpenAIRE |
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