Effects of a liquid diet on the response properties of temporomandibular joint nociceptive neurons in the trigeminal subnucleus caudalis of growing rats
| Autor: | Mai Shibata, Satoshi Kokai, Takayoshi Ishida, Koichi Fujita, Maya Hiranuma, Satomi Naito, Takashi Ono, Tadachika Yabushita |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Liquid diet Orthodontics Sensory system Biology Synaptic Transmission Random Allocation Trigeminal Caudal Nucleus Evoked Potentials Somatosensory Physical Stimulation Internal medicine Neural Pathways Male rats medicine Animals Nociceptive Neurons Weaning Trigeminal Nerve Rats Wistar Food Formulated Temporomandibular Joint Nociceptors Electric Stimulation Biomechanical Phenomena Rats Temporomandibular joint medicine.anatomical_structure Endocrinology Otorhinolaryngology Touch Anesthesia Surgery Neuron Oral Surgery Mechanoreceptors Joint Capsule |
| Zdroj: | Orthodontics & Craniofacial Research. |
| ISSN: | 1601-6335 |
| DOI: | 10.1111/ocr.12023 |
| Popis: | Structured Abstract Objective To investigate whether low mechanical loading on the temporomandibular joint (TMJ) when ingesting a liquid diet affects the response properties of neurons in the trigeminal spinal tract subnucleus caudalis (Sp5C) in growing rats. Materials and Methods Shortly after weaning, 2-week-old male rats were fed chow pellets (control) or a liquid diet (experimental). Firing activities of single sensory units were recorded from the Sp5C at 4, 5, 7, and 9 weeks. Neurons were functionally classified by their responsiveness to TMJ stimuli. The responses of Class II and III neurons to TMJ stimuli were investigated. Results In both neuron classes, the firing threshold in the experimental group was significantly lower than in the control group at all time points, but remained static in the control group throughout the experimental period, whereas it peaked in the experimental group at 4 weeks, decreased at 5 weeks, and remained stable thereafter until 9 weeks. Similarly, the initial firing frequency was significantly higher in the experimental group than in the control group, but remained static in the control group throughout the experimental period, whereas in the experimental group, it was at its lowest at 4 weeks, increased at 5 weeks, and stayed stable thereafter until 9 weeks. Conclusion Differences in TMJ loading arising from variable diet consistency during growth may affect the functional characteristics of Sp5C neurons. |
| Databáze: | OpenAIRE |
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