Biochemical follow‐up of nonfunctioning benign thyroid nodules
| Autor: | Yasaman Mohtasebi, Terry Cheuk-Fung Yip, Raafia Memon, Elizabeth M. Lamos, Laurence S. Magder, Silvia R. Salgado Nunez del Prado, Kashif M. Munir |
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| Rok vydání: | 2020 |
| Předmět: |
Thyroid nodules
endocrine system medicine.medical_specialty endocrine system diseases Endocrinology Diabetes and Metabolism Thyrotropin 030209 endocrinology & metabolism Gastroenterology 03 medical and health sciences 0302 clinical medicine Endocrinology Hypothyroidism Thyroid-stimulating hormone Internal medicine medicine Humans Thyroid Nodule Retrospective Studies Subclinical infection business.industry Incidence (epidemiology) Thyroid Retrospective cohort study Nodule (medicine) medicine.disease medicine.anatomical_structure 030220 oncology & carcinogenesis medicine.symptom business hormones hormone substitutes and hormone antagonists Follow-Up Studies Hormone |
| Zdroj: | Clinical Endocrinology. 94:322-329 |
| ISSN: | 1365-2265 0300-0664 |
| Popis: | OBJECTIVE For the biochemical follow-up of benign thyroid nodules, some authors recommend periodic lifelong measurement of thyroid-stimulating hormone (TSH) to assess for the development of toxic nodules over time. The purpose of this retrospective study was to assess the incidence of thyroid dysfunction over time in patients with benign thyroid nodule(s), with a normal TSH at diagnosis and to identify any factors that may predict biochemical dysfunction over time. METHODS Medical records of patients with the diagnosis of thyroid nodule(s) between January 2011 and August 2014 were reviewed. Patients who had TSH measurement within 1 year of initial diagnostic ultrasound (US) were included. RESULTS One-hundred fifty-seven patients identified with thyroid nodule(s) satisfied inclusion criteria. At a median follow-up of 45 (34-63) months, 13 (8.3%) patients developed thyroid dysfunction. The mean initial TSH in the group which developed subclinical hyperthyroidism (0.65 mIU/mL) was statistically different from the group that did not develop thyroid dysfunction (1.37 mIU/mL, P: 0.007). More patients with TSH |
| Databáze: | OpenAIRE |
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