Correlation of reversion-inducing cysteine-rich protein with kazal motifs (RECK) and extracellular matrix metalloproteinase inducer (EMMPRIN), with MMP-2, MMP-9, and survival in colorectal cancer

Autor: Thijs Hendriks, Michel F.P. van der Jagt, Theo Wobbes, Paul N. Span, Fred C.G.J. Sweep, Erwin T. Waas, Audrey H.H. Merry, Theo J.M. Ruers
Rok vydání: 2006
Předmět:
Male
Cancer Research
Time Factors
Colorectal cancer
Cell Survival
Reversion
Aetiology
screening and detection [ONCOL 5]
Matrix metalloproteinase
GPI-Linked Proteins
Kazal Motifs
Extracellular matrix
Immune Regulation [NCMLS 2]
Translational research [ONCOL 3]
medicine
Gelatinase
Humans
Genetic Predisposition to Disease
RNA
Messenger
Survival analysis
Metalloproteinase
Membrane Glycoproteins
Hereditary cancer and cancer-related syndromes [ONCOL 1]
Chemistry
Endocrinology and reproduction [UMCN 5.2]
Hormonal regulation [IGMD 6]
medicine.disease
Prognosis
Pathogenesis and modulation of inflammation [N4i 1]
Tumor microenvironment [UMCN 1.3]
Treatment Outcome
Oncology
Matrix Metalloproteinase 9
Evaluation of complex medical interventions [NCEBP 2]
Cancer research
Basigin
Disease Progression
Matrix Metalloproteinase 2
Female
Colorectal Neoplasms
Zdroj: Cancer Letters, 237, 2, pp. 289-97
Cancer Letters, 237, 289-97
ISSN: 0304-3835
Popis: Contains fulltext : 51160.pdf (Publisher’s version ) (Closed access) mRNA, and latent and active levels MMP-2 and -9 were higher in tumor tissue compared to normal tissue from 63 patients with colorectal cancer, whereas RECK and EMMPRIN levels were lower. Correlations between mRNA, latent, and active MMP were particular high for MMP-2 in tumor tissue (R(s)=0.6-0.8, P
Databáze: OpenAIRE
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