Utility of serum free light chain measurements in multiple myeloma patients not achieving complete response to therapy

Autor:	Francis K. Buadi, Robert A. Kyle, Yi Lisa Hwa, Suzanne R. Hayman, John A. Lust, Morie A. Gertz, David Dingli, Shaji Kumar, M Alhaj Moustafa, Martha Q. Lacy, Angela Dispenzieri, Prashant Kapoor, S V Rajkumar
Rok vydání:	2015
Předmět:	Adult Male Cancer Research medicine.medical_specialty Urology Immunoglobulin light chain survival Article Text mining Serum free Antineoplastic Combined Chemotherapy Protocols medicine Humans Complete response Multiple myeloma Aged Neoplasm Staging Retrospective Studies Aged 80 and over response serum free light chain ratio business.industry Remission Induction Hematology Middle Aged Prognosis medicine.disease 3. Good health Surgery Survival Rate multiple myeloma Measurable Disease medicine.anatomical_structure Oncology Monoclonal Female Immunoglobulin Light Chains Bone marrow Neoplasm Recurrence Local business Follow-Up Studies
Zdroj:	Leukemia
ISSN:	1476-5551 0887-6924
DOI:	10.1038/leu.2015.118
Popis:	Normalization of the serum free light chain ratio (FLCr) with the absence of bone marrow monoclonal plasma cells following achievement of a complete response (CR) to therapy denotes a stringent CR in multiple myeloma (MM), and is associated with improved overall survival (OS). However, its value in patients achieving
Databáze:	OpenAIRE
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