Systemic histiocytosis presenting as multiple sclerosis
Autor: | Joseph A. Frank, Jonathan O. Harris, Conrad V. Kufta, Mary E. Smith, Dale E. McFarlin, David A. Katz |
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Rok vydání: | 1993 |
Předmět: |
Male
medicine.medical_specialty Pathology Multiple Sclerosis Biopsy medicine.medical_treatment Diagnostico diferencial Bone and Bones Diagnosis Differential Central nervous system disease Partial response Glial Fibrillary Acidic Protein Humans Medicine Radionuclide Imaging Progressive multiple sclerosis Brain Diseases medicine.diagnostic_test business.industry Multiple sclerosis Brain Histiocytes Magnetic resonance imaging Middle Aged medicine.disease Immunohistochemistry Magnetic Resonance Imaging Dermatology Radiography Radiation therapy Histiocytosis Neurology Neurology (clinical) business Follow-Up Studies |
Zdroj: | Annals of Neurology. 33:549-554 |
ISSN: | 1531-8249 0364-5134 |
Popis: | A patient resembling one with progressive multiple sclerosis in clinical presentation and by magnetic resonance imaging was studied in detail. Some features atypical for multiple sclerosis prompted a persistent search for an alternative cause. The diagnosis of a non-Langerhans systemic histiocytosis involving brain and bone was established and showed a partial response to radiation therapy. This patient illustrates the continued importance of a broad approach to the evaluation of possible multiple sclerosis, with particular attention to atypical features. |
Databáze: | OpenAIRE |
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