Gestational iron deficiency anemia is associated with preterm birth, fetal growth restriction, and postpartum infections
| Autor: | Mirjami M. Mattila, Nanneli Pallasmaa, Lotta Kemppinen, Leila Varakas, Ari Törmä, Kaarin Mäkikallio, Eeva Ekholm |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Iron Administration Oral Hemoglobins 03 medical and health sciences 0302 clinical medicine Pregnancy Oral administration Outcome Assessment Health Care Fetal growth medicine Humans 030212 general & internal medicine Postpartum infections Fetal Growth Retardation 030219 obstetrics & reproductive medicine Anemia Iron-Deficiency business.industry Obstetrics Pregnancy Complications Hematologic Infant Newborn Pregnancy Outcome Outcome measures Obstetrics and Gynecology medicine.disease Trace Elements Iron-deficiency anemia Neonatal outcomes Pediatrics Perinatology and Child Health Iron supplementation Premature Birth Puerperal Infection Gestation Administration Intravenous Female business |
| Zdroj: | Journal of Perinatal Medicine. 49:431-438 |
| ISSN: | 1619-3997 0300-5577 |
| DOI: | 10.1515/jpm-2020-0379 |
| Popis: | Objectives Gestational IDA has been linked to adverse maternal and neonatal outcomes, but the impact of iron supplementation on outcome measures remains unclear. Our objective was to assess the effects of gestational IDA on pregnancy outcomes and compare outcomes in pregnancies treated with either oral or intravenous iron supplementation. Methods We evaluated maternal and neonatal outcomes in 215 pregnancies complicated with gestational IDA (Hb Results Gestational IDA was associated with an increased risk of preterm birth (10.2% vs. 6.1%, p=0.009) and fetal growth restriction (FGR) (1.9% vs. 0.3%, p=0.006). The gestational IDA group that received intravenous iron supplementation had a greater increase in Hb levels compared to those who received oral medication (18.0 g/L vs. 10.0 g/L, p Conclusions Compared to the reference group, prematurity, FGR, postpartum infections, and extended hospital stays were more common among mothers with gestational IDA, causing an additional burden on the families and the healthcare system. |
| Databáze: | OpenAIRE |
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