Risk of preeclampsia in of women who underwent chorionic villus sampling
| Autor: | Giuseppe Castaldo, Gabriele Saccone, Pasquale Martinelli, Laura Sarno, Giuseppe Maria Maruotti, Fulvio Zullo, Antonia Giudicepietro, Vincenzo Berghella |
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| Přispěvatelé: | Maruotti, Giuseppe Maria, Giudicepietro, Antonia, Saccone, Gabriele, Castaldo, Giuseppe, Sarno, Laura, Zullo, Fulvio, Berghella, Vincenzo, Martinelli, Pasquale |
| Rok vydání: | 2018 |
| Předmět: |
Adult
medicine.medical_specialty hypertension Chorionic villus sampling Lower risk Risk Assessment Severity of Illness Index Preeclampsia preeclampsia Young Adult 03 medical and health sciences fluids and secretions 0302 clinical medicine Pre-Eclampsia Pregnancy medicine Humans 030212 general & internal medicine reproductive and urinary physiology Retrospective Studies 030219 obstetrics & reproductive medicine medicine.diagnostic_test Obstetrics business.industry Incidence (epidemiology) Obstetrics and Gynecology Odds ratio equipment and supplies medicine.disease female genital diseases and pregnancy complications Confidence interval Pregnancy Trimester First Chorionic Villi Sampling CVS Case-Control Studies embryonic structures Pediatrics Perinatology and Child Health Gestation Female business Cohort study |
| Zdroj: | The Journal of Maternal-Fetal & Neonatal Medicine. 32:3012-3015 |
| ISSN: | 1476-4954 1476-7058 |
| Popis: | OBJECTIVE: To assess the risk of preeclampsia in women who underwent chorionic villus sampling (CVS). STUDY DESIGN: This is a retrospective, single-center, cohort study. All consecutive singleton gestations who underwent chorionic villus sampling from January 2014 to January 2016 were included in the study. The primary outcome was the incidence of preeclampsia. Subgroup analysis in women with beta thalassemic trait was performed. Logistic regression, presented as adjusted odds ratio (aOR) with the 95% of confidence interval (CI), was performed. RESULTS: Five hundred forty-seven women who underwent CVS, and 1532 women who did not were analyzed. Women who underwent CVS had a significantly lower risk of preeclampsia (4.4 versus 8.0%; aOR 0.53, 95%CI 0.34-0.83), and late-onset preeclampsia (3.3 versus 6.1%; aOR 0.52, 95%CI 0.31-0.87). No statistically significant differences were found in preeclampsia with severe features, early-onset preeclampsia, and preterm birth (PTB). Women who underwent CVS due to thalassemic trait had a lower incidence of preeclampsia compare to those women who did not undergo CVS (3.3 versus 8.0%; aOR 0.39, 95%CI 0.14-0.87), while no differences were found comparing women who underwent CVS due to thalassemic trait with women who underwent CVS due to other reasons. CONCLUSIONS: Women who underwent first trimester CVS had a lower risk of preeclampsia compared to those who did not. |
| Databáze: | OpenAIRE |
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