Evaluation of a new lateral flow test for detection of Streptococcus pneumoniae and Legionella pneumophila urinary antigen
Autor: | Pernille L. Elverdal, Ian C. Skovsted, Søren A. Uldum, Charlotte Sværke Jørgensen, Jesper F. Sørensen, Sanne Otte |
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Rok vydání: | 2015 |
Předmět: |
Adult
Microbiology (medical) Urinary system Point-of-care testing medicine.disease_cause Sensitivity and Specificity Microbiology Legionella pneumophila Lateral flow test Antigen Streptococcus pneumoniae Humans Medicine Molecular Biology Aged Aged 80 and over Antigens Bacterial biology business.industry Middle Aged Pneumonia Pneumococcal biology.organism_classification medicine.disease respiratory tract diseases Pneumonia Point-of-Care Testing Female Reagent Kits Diagnostic Legionnaires' Disease business Infectious agent |
Zdroj: | Journal of Microbiological Methods. 116:33-36 |
ISSN: | 0167-7012 |
Popis: | Pneumonia is a major cause of morbidity and mortality worldwide. Early diagnosis of the etiologic agent is important in order to choose the correct antibiotic treatment. In this study we evaluated the first commercial combined test for the agents of pneumococcal pneumonia and Legionnaires' disease based on urinary antigen detection, the ImmuView® Streptococcus pneumoniae and Legionella pneumophila Urinary Antigen Test. In this evaluation, the new test had a significantly higher sensitivity than the BinaxNOW® lateral flow tests and the Binax® EIA test. This identifies the ImmuView® S. pneumoniae and L. pneumophila Urinary Antigen Test as a fast and sensitive point of care test for identification of the infectious agent in a major group of patients with pneumonia. |
Databáze: | OpenAIRE |
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