First-Line Antimicrobial Resistance Patterns of Escherichia coli in Children With Urinary Tract Infection in Emergency Department and Primary Care Clinics

Autor: Ann Frederick, Elisabeth Lawler, M. Nadeem Ahmed, Debby Vannoy, Sandy Chang
Rok vydání: 2015
Předmět:
0301 basic medicine
Male
Pediatrics
medicine.medical_specialty
Adolescent
Urinary system
030106 microbiology
Primary care
Microbial Sensitivity Tests
Urinalysis
urologic and male genital diseases
medicine.disease_cause
03 medical and health sciences
0302 clinical medicine
Antibiotic resistance
Risk Factors
030225 pediatrics
Ampicillin
Drug Resistance
Bacterial
Trimethoprim
Sulfamethoxazole Drug Combination
medicine
Escherichia coli
Humans
Child
Escherichia coli Infections
Retrospective Studies
Primary Health Care
Genitourinary system
business.industry
Infant
Newborn
Infant
Emergency department
bacterial infections and mycoses
female genital diseases and pregnancy complications
Confidence interval
Anti-Bacterial Agents
Cross-Sectional Studies
Treatment Outcome
Child
Preschool
Pediatrics
Perinatology and Child Health
Urinary Tract Infections
Female
Illinois
business
Emergency Service
Hospital
medicine.drug
Zdroj: Clinical pediatrics. 55(1)
ISSN: 1938-2707
Popis: Objective: To identify risk factors for antibiotic resistance to Escherichia coli ( E. coli) in children with urinary tract infections (UTIs) in emergency room and primary care clinics. Method: This is a cross-sectional study of children 0 to 18 years of age reported to have E coli–positive UTIs whose medical and laboratory records were systematically reviewed. Result: Compared with girls, boys were 2.29 times (confidence interval [CI] = 1.30-4.02) more likely to have E coli isolates resistant to ampicillin and 2 times more likely (CI = 1.13-3.62) to have isolates resistant to trimethoprim-sulfamethoxazole (TMP/SMX). Patients with genitourinary abnormalities were 1.57 times more likely to be resistant to ampicillin (CI = 1.03-2.41) and 1.86 times to TMP/SMX (CI = 1.18-2.94). Conclusion: Higher rates of ampicillin and TMP/SMX resistant urinary E coli isolates were observed among boys and children with a history of genitourinary abnormality. Age and recent antibiotic prescription are also potential risk factors for resistance.
Databáze: OpenAIRE
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