A Potential Novel Indication for Preventing Thromboembolism in Patients with Atrial Arrhythmias: Remodeling of the Left Atrium
| Autor: | Chen Liu, Yu-long Guo, Shuang Liu, Hui Li |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Left atrium Risk Assessment Biochemistry Risk Factors Left atrial Thromboembolism Internal medicine Atrial Fibrillation Genetics medicine Humans In patient Heart Atria Risk factor business.industry Anticoagulants Atrial fibrillation Atrial Remodeling Thromboembolism Prophylaxis Atrial arrhythmias Prognosis medicine.disease Thrombosis medicine.anatomical_structure Cardiology business |
| Zdroj: | Current Medical Science. 41:1187-1191 |
| ISSN: | 2523-899X 2096-5230 |
| DOI: | 10.1007/s11596-021-2449-4 |
| Popis: | OBJECTIVE Thrombosis in patients with atrial arrhythmias might be associated with remodeling of the left atrium (LA). We aimed to describe this relationship and identify a novel factor, in addition to the CHA2DS2-VASc score, to guide therapeutic strategies for preventing thromboembolism in the hope of improving the prognosis for such patients. METHODS Patients diagnosed with atrial arrhythmias and who met our inclusion criteria were enrolled in this study. Various clinical parameters were recorded; diameters reflecting remodeling of the LA were measured and thrombosis was diagnosed by enhanced CT. RESULTS Totally, 192 patients were enrolled in the study. The overall prevalence of left atrial thrombosis was 8.3%. Patients with persistent atrial fibrillation exhibited the highest anteroposterior diameter of the LA (45.1±7.2 mm) and prevalence of thrombosis (15.6%). An anteroposterior LA diameter of ≥50 mm was a strong independent impact risk factor for thrombosis (OR=10.1, 95%CI: 2.8-36.9, P |
| Databáze: | OpenAIRE |
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