Xanthoma in the external acoustic meatus
| Autor: | L.L. Veder, A. Duvekot, V. van Dis |
|---|---|
| Přispěvatelé: | Otorhinolaryngology and Head and Neck Surgery, Pathology |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
RD1-811 Head and neck area Xanthoma Pediatrics RJ1-570 03 medical and health sciences 0302 clinical medicine Normolipemic medicine In patient Ear canal Head and neck Lipoprotein metabolism business.industry medicine.disease Dermatology External Acoustic Meatus medicine.anatomical_structure Hematologic disease 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health 030211 gastroenterology & hepatology Foamy cells Surgery Presentation (obstetrics) business Pediatric population |
| Zdroj: | Journal of Pediatric Surgery Case Reports, 69:101862. Elsevier Journal of Pediatric Surgery Case Reports, Vol 69, Iss, Pp 101862-(2021) |
| ISSN: | 2213-5766 |
| Popis: | Objectivesa unique case of a xanthoma in the external ear canal of a pediatric patient is presented in this case report. We describe and resume the current literature on xanthomas in the head and neck area.Methodsclinical and intraoperative findings are reported and the presumed mechanisms for the emergence of xanthomas are discussed. We furthermore described the pathologic and immunohistochemical characteristics.Resultsxanthomas are mostly seen in patients with lipid metabolism disorders or hyperlipidemia. However, they can be present in normolipemic patients and are also associated with hematologic disease. Literature on the existence of xanthomata in the head and neck area is rare and there are no case reports in the pediatric population to the best of our knowledge. Besides the clinical presentation, characteristic histopathological features can confirm the diagnosis. When features are overlapping, immunohistochemistry can be necessary.Conclusionsince different subtypes of xanthoma have specific clinical and histopathological features and are associated with typical underlying disease, in our opinion histopathologic confirmation, especially in the pediatric patient, is important. This enables accurate referral to a specialized clinician to identify and eventually treat the underlying metabolic or hematologic disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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