Retention of Dinoprostone Vaginal Insert Beyond 12 Hours for Induction of Labor
| Autor: | William F. Rayburn, Leo Pevzner, Barbara L. Powers, Deborah A. Wing, Matthew C. Brennan |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Adult
Time Factors medicine.medical_treatment Cervix Uteri Oxytocin Labor Complication Dinoprostone law.invention Young Adult Randomized controlled trial Pregnancy law Oxytocics Intensive care Humans Medicine Labor Induced Cesarean delivery Vaginal insert Retrospective Studies business.industry Infant Newborn Obstetrics and Gynecology Heart Rate Fetal Induction of labor Administration Intravaginal Delayed-Action Preparations Anesthesia Labor induction Pediatrics Perinatology and Child Health Apgar Score Female business |
| Zdroj: | American Journal of Perinatology. 28:479-484 |
| ISSN: | 1098-8785 0735-1631 |
| DOI: | 10.1055/s-0030-1271208 |
| Popis: | We evaluate the likelihood of cesarean delivery and identify risks of retaining a sustained-release dinoprostone vaginal insert beyond 12 hours. In a secondary analysis of outcomes, data were collected during a large, randomized trial comparing different sustained-release prostaglandin vaginal inserts for labor induction. Outcomes were compared between cases in whom the dinoprostone insert was removed early (within 12 hours) or late (12 to 24 hours). A total of 431 subjects had the dinoprostone vaginal insert in place for 12 to 24 hours ( N = 226, 52.4%) or within 12 hours ( N = 205, 47.6%). Insert removal for labor complications was less frequent in the late group than in the early group (5.8% versus 21.5%; P ≤ 0.001). Abnormal uterine contractility patterns were less common in the late than early group (25.2% versus 37.6%; P = 0.03). Rates of cesarean delivery during the first hospitalization were similar for late and early groups (25.0% versus 29.2%; P = 0.33). Percentages of infants requiring immediate attention or intensive care were low and similar between groups. Sustained-release intravaginal dinoprostone left in place beyond 12 hours did not increase the risks of intrapartum complications, cesarean delivery, or immediate adverse neonatal events. |
| Databáze: | OpenAIRE |
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