The relationship between uterine prolapse and premalignant endometrial pathology

Autor: Ebru Şahin Güleç, Serkan Guclu, Esin Celik, Fatma Eskicioglu, E Bahar Gur, Seçil Kurtulmuş, Mine Genc
Rok vydání: 2016
Předmět:
Zdroj: Clinical and Experimental Obstetrics & Gynecology. 43:500-503
ISSN: 0390-6663
DOI: 10.12891/ceog2095.2016
Popis: Objective The aim of this study was to stress the importance of performing a thorough uterine assessment before selecting an organ- sparing surgery in patients presenting with uterine prolapse and no other complaints. Materials and methods This study included a total of 111 participants who presented with pelvic organ prolapse and underwent hysterectomy for grades 3-4 uterine prolapse. The posthysterectomy histopathology results were classified as benign (atrophic endometrium, proliferative or secretory endometrium) or pathologic (endometrial hyperplasia, endometrial polyp, adenomyosis, myoma uteri, and endometrium carcinoma). Results Of the 111 patients enrolled in this study, 23 (20.2%) had endometrial hyperplasia, eight (7.2%) had endometrial polyps, 30 (27%) had uterine fibroids, and 20 (18%) had adenomyosis. Conclusion There may be premalignant lesions of the endometrium in both premenopausal and postmenopausal women presenting with uterine prolapse and no other symptoms. A chronic inflammatory process resulting from the extra-vaginal location of the uterus may play a role in the development of these lesions. Further studies are needed on this subject.
Databáze: OpenAIRE