Problems Associated with Biological Markers of Alzheimer’s Disease
| Autor: | Kari M. Mattila, Tuula Pirttilä, H. Frey, M. A. Korolainen |
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| Rok vydání: | 2005 |
| Předmět: |
Diagnostic Imaging
Proteomics medicine.medical_specialty Neurology General Medicine Neuropathology Disease Biology Biochemistry Cellular and Molecular Neuroscience Neuroimaging Alzheimer Disease medicine Humans Electrophoresis Gel Two-Dimensional Neurochemistry Differential diagnosis Neuroscience Biomarkers |
| Zdroj: | Neurochemical Research. 30:1501-1510 |
| ISSN: | 1573-6903 0364-3190 |
| DOI: | 10.1007/s11064-005-8827-7 |
| Popis: | The etiopathogenesis of Alzheimer's disease (AD) is still unclear, although clinical diagnostic criteria exist and the neuropathology of AD has been studied in great detail during the last 20 years. The present study addresses certain problems in the search for biological markers for the diagnosis, as well as in the follow-up of the course of AD and its differential diagnosis and reports some of our own observations in comparison with other studies. These include protein, genetic and neuroimaging markers. The definitions of biological markers and search strategies are also discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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