Additional file 1 of Total serum N-glycans associate with response to immune checkpoint inhibition therapy and survival in patients with advanced melanoma

Autor: Visconti, Alessia, Rossi, Niccolò, Deriš, Helena, Lee, Karla A, Hanić, Maja, Trbojević-Akmačić, Irena, Thomas, Andrew M., Bolte, Laura A., Björk, Johannes R., Hooiveld-Noeken, Jahlisa S., Board, Ruth, Harland, Mark, Newton-Bishop, Julia, Harries, Mark, Sacco, Joseph J., Lorigan, Paul, Shaw, Heather M., de Vries, Elisabeth G.E., Fehrmann, Rudolf S.N., Weersma, Rinse K., Spector, Tim D., Nathan, Paul, Hospers, Geke A. P., Sasieni, Peter, Bataille, Veronique, Lauc, Gordan, Falchi, Mario
Rok vydání: 2023
DOI: 10.6084/m9.figshare.22613741
Popis: Additional file 1: Figure 1. Representative chromatogram of total human plasma/serum N-glycome separated byHILIC-UPLC into 39 N-glycan peaks (GP1-GP39). Figure 2. Swimmer plot for the 88 patients with advanced melanoma included in this study. Figure 3. Pearson's correlation among the measured N-glycan and derived traits associated with overall response rate in 88 patients with advanced melanoma. Figure 4. Significant association between directly measured serum N-glycans and overall response rate. Figure 5. Kaplan-Meier progression-free survival curves in 88 patients with advanced melanoma (directly measured N-glycans). Figure 6. Diagnostic plots for Cox proportional hazards regression model of survival time on sex, age at diagnosis of advanced melanoma, BMI, dichotomized LDH levels, and ECOG performance-status. Figure 7. Kaplan-Meier overall survival curves in 88 patients with advanced melanoma (directly measured N-glycans).
Databáze: OpenAIRE