Variability in the prescription of biological drugs in rheumatoid arthritis in Spain: a multilevel analysis

Autor: Desiree Ruiz Vilchez, MIGUEL ANGEL BELMONTE-SERRANO, María Montoro, Bonifacio Alvarez-Lario, Rodriguez Heredia Jose Manuel, Pilar Font Ugalde, Antonio Naranjo Hernandez, Eduardo Collantes Estévez, Joan Calvet
Rok vydání: 2018
Předmět:
Zdroj: Rheumatology International. 38:589-598
ISSN: 1437-160X
0172-8172
DOI: 10.1007/s00296-018-3933-4
Popis: To describe variability in the prescription of biologics (B-DMARDs) for patients with rheumatoid arthritis (RA) in hospitals in Spain, and to explore which characteristics of the patient, the doctor and the hospital are associated with this variability. Cross-sectional multicentric study in 46 rheumatology services of the National Health System. Medical records of 1188 randomly selected patients were reviewed. The association of each variable with B-DMARD prescription was analyzed using simple logistic regressions. Multilevel logistic regression models were created to analyze variability among centers. 36.8% of patients had received B-DMARD. The proportion of patients being treated with B-DMARDs varied between 3.6 and 71.4% depending on the center. Association of prescription of B-DMARD with patient age (OR = 0.958, 95% CI = 0.947-0.968, p
Databáze: OpenAIRE