Endorectal ultrasonography, strain elastography and MRI differentiation of rectal adenomas and adenocarcinomas
| Autor: | Sabine Leh, Jo Erling Riise Waage, Cornelia Rösler, Frank Pfeffer, Simon P. Bach, Roald Flesland Havre, Gunnar Baatrup, Svein Ødegaard, Ingfrid S. Haldorsen |
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| Rok vydání: | 2014 |
| Předmět: |
Adenoma
Adult Male medicine.medical_specialty Strain elastography Elasticity Imaging Techniques/methods Adenoma/diagnosis Rectal Neoplasms/diagnosis Sensitivity and Specificity Magnetic Resonance Imaging/methods Endosonography Diagnosis Differential Endosonography/methods medicine Humans Prospective Studies Aged Rectum/diagnostic imaging Aged 80 and over adenocarcinoma Strain (chemistry) business.industry Rectal Neoplasms Gastroenterology Rectum Original Articles endorectal ultrasound Middle Aged Magnetic Resonance Imaging strain elastography Adenocarcinoma/diagnosis adenoma Elasticity Imaging Techniques Female Radiology business Endorectal ultrasonography MRI |
| Zdroj: | Colorectal Disease Europe PubMed Central Waage, J E R, Leh, S, Røsler, C, Pfeffer, F, Bach, S P, Havre, R F, Haldorsen, I S, Odegaard, S & Baatrup, G 2015, ' Endorectal ultrasonography, strain elastography and MRI differentiation of rectal adenomas and adenocarcinomas ', Colorectal Disease, vol. 17, no. 2, pp. 124–131 . https://doi.org/10.1111/codi.12845 |
| ISSN: | 1463-1318 |
| DOI: | 10.1111/codi.12845 |
| Popis: | Aim Strain elastography is a method for recording tissue hardness. Strain in different areas may be compared using strain ratio (SR). The aims of this study were to validate a previously proposed SR cut-off value of 1.25 for differentiating adenocarcinomas from adenomas and to compare the performance of endorectal ultrasonography (ERUS), strain elastography and MRI in the same patients. Method A prospective evaluation of 120 consecutive patients with rectal neoplasia, using a predetermined elastography strain ratio cut-off value, was performed to differentiate adenomas from adenocarcinomas. ERUS and MRI were performed according to standard routine at Haukeland University Hospital, defining T0 as adenomas and T1–T4 as adenocarcinomas. Subsequent histopathology was used as the reference standard. Results Histopathological evaluation revealed 21 adenomas and 99 adenocarcinomas. Sensitivity, specificity and accuracy (with 95% CI) were as follows: ERUS: 0.96 (0.90–0.99), 0.62 (0.40–0.80) and 0.90 (0.83–0.94); elastography SR: 0.96 (0.90–0.99), 0.86 (0.66–0.96) and 0.94 (0.88–0.97); and MRI: 0.99 (0.94–1.00), 0.07 (0.00–0.31) and 0.87 (0.80–0.93). Conclusion This study confirms that the elastography SR assessment accurately differentiates sessile adenomas from adenocarcinomas. SR assessment has a superior ability to differentiate adenomas and adenocarcinomas when compared with ERUS and MRI. MRI examination seems unable to recognize adenomas and should be interpreted with care when early-stage rectal neoplasia is suspected. publishedVersion |
| Databáze: | OpenAIRE |
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