Procalcitonin as an early marker in the detection of intestinal anastomotic leakage, in a university hospital from Bogotá
Autor: | Benítez Navarrete, Elkin Eduardo, Mosquera González, Maria Fernanda, Martinez Rojas, Valeria, Beltrán García, Tatiana Carolina |
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Přispěvatelé: | Figueroa Avendaño, Carlos Edgar |
Jazyk: | Spanish; Castilian |
Rok vydání: | 2020 |
Předmět: |
Diagnóstico no invasivo
Fístula anastomótica Anastomotic fistula Procalcitonina-Diagnóstico de laboratorio Detección temprana Early detection Complicaciones postoperatorias Early diagnosis Cirugía de los intestinos Procalcitonina Complicaciones postoperatorias-Diagnóstico temprano Postoperative Complications Colorectal surgery Diagnóstico temprano Cirugía colorectal Peritonitis-Diagnóstico temprano Procalcitonin Incidencia & prevención de la enfermedad |
Zdroj: | Giaccaglia V, Salvi PF, Cunsolo GV, Sparagna A, Antonelli MS, Nigri G, et al. Procalcitonin, as an early biomarker of colorectal anastomotic leak, facilitates enhanced recovery after surgery. Journal of Critical Care. 2014 Aug;29(4):528–32. Lagoutte N, Facy O, Ravoire A, Chalumeau C, Jonval L, Rat P, et al. C-reactive protein and procalcitonin for the early detection of anastomotic leakage after elective colorectal surgery: Pilot study in 100 patients. Journal of Visceral Surgery. 2012 Oct;149(5):e345–9. Giaccaglia V, Salvi PF, Antonelli MS, Nigri G, Pirozzi F, Casagranda B, et al. Procalcitonin Reveals Early Dehiscence in Colorectal Surgery: The PREDICS Study. Annals of Surgery. 2016 May;263(5):967–72. Ramos Fernández M, Rivas Ruiz F, Fernández López A, Loinaz Segurola C, Fernández Cebrián JM, de la Portilla de Juan F. Proteína C reactiva como predictor de fuga anastomótica en cirugía colorrectal. Comparación entre cirugía abierta y laparoscópica. Cirugía Española. 2017 Nov;95(9):529–35. Mirnezami A, Mirnezami R, Chandrakumaran K, Sasapu K, Sagar P, Finan P. Increased Local Recurrence and Reduced Survival From Colorectal Cancer Following Anastomotic Leak: Systematic Review and Meta-Analysis. Annals of Surgery. 2011 May;253(5):890–9. Bosmans JWAM, Jongen ACHM, Bouvy ND, Derikx JPM. Colorectal anastomotic healing: why the biological processes that lead to anastomotic leakage should be revealed prior to conducting intervention studies. BMC Gastroenterology [Internet]. 2015 Dec [cited 2019 Nov 20];15(1). Available from: http://www.biomedcentral.com/1471-230X/15/180 Skandalakis JE. Skandalakis’ cirugía: bases de la anatomía quirúrgica. Madrid: Marbán; 2015 Hayati F, Mohd Azman ZA, Nasuruddin DN, Mazlan L, Zakaria AD, Sagap I. Serum Procalcitonin Predicts Anastomotic Leaks in Colorectal Surgery. Asian Pac J Cancer Prev. 2017 27;18(7):1821–5. Pacheco MA, Aldana GE, Martínez LE, Forero JC, Gómez CA, Coral EM, et al. 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DOI: | 10.48713/10336_20913 |
Popis: | Introducción: La fuga anastomótica, es una complicación de las anastomosis intestinales con una incidencia del 2-7% en los centros de experiencia(1). Para lograr una detección precoz se incluyen los marcadores serológicos como la Procalcitonina(2). Métodos: Cohorte retrospectiva, pacientes llevados a cirugía colorectal con anastomosis intestinal, el objetivo es estimar asociación de procalcitonina (≥2ng/dL) cómo marcador inflamatorio temprano y la fuga anastomótica, en Servicio de Coloproctología de hospital de cuarto nivel, entre Septiembre 2017 y Enero 2019. Resultados: Cohorte de 237 pacientes, 51% mujeres (18-89 años), con comorbilidades en el 81%, incluyendo inmunosupresión, cáncer de colon fue la patología más operada (53,1%). El abordaje laparoscópico el más aplicado 60,34%, anastomosis colorrectal la más realizada (47,26%). Anastomosis ileocolónica presentó mayor frecuencia 43,75% de dehiscencia. La fuga anastomótica esta asociada a procalcitonina sérica positiva al 3 día postoperatorio (X2: 8,68, gl:1, valor p |
Databáze: | OpenAIRE |
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