Social Determinants of Health and Oral Cavity Cancer Treatment and Survival: A Competing Risk Analysis

Autor: Pratima Agarwal, Eric A. Jones, Anand K. Devaiah, Ravi Agrawal
Rok vydání: 2019
Předmět:
Zdroj: The Laryngoscope. 130:2160-2165
ISSN: 1531-4995
0023-852X
Popis: OBJECTIVE Competing risk analysis is a powerful assessment for cancer risk factors and covariates. This method can better elucidate insurance status and other social determinants of health covariates in oral cavity cancer treatment, survival, and disparities. STUDY DESIGN Retrospective cohort study using the Surveillance, Epidemiology, and End Results (SEER) database. METHODS Data regarding patient characteristics, clinical stage at diagnosis, treatment, and survival data for 20,271 patients diagnosed with oral cavity cancer was extracted from the SEER 18 Regs Research Data including Hurricane Katrina Impacted Louisiana Cases from 1973 to 2014. All statistical analyses were performed using SAS 9.5 (SAS Institute Inc., Cary, NC). The Fine-Gray method for assessing impact, risk, and covariates was employed. RESULTS Medicaid patients presented with later stage disease, larger tumor size, more distant metastases, and more lymph node involvement at diagnosis compared to insured patients. Medicaid patients were less likely to receive cancer-directed surgery. Medicaid status was also associated with worse cancer-specific survival (subhazard ratios 1.87, 95% confidence interval 1.72-2.04, P
Databáze: OpenAIRE